Reaction mass of 4-(2,6,6-trimethylcyclohex-2-ene-1-yl)-but-3-ene-2-one and 4-(2,6,6-trimethylcyclohex-1-ene-1-yl)-but-3-ene-2-one

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Data is from study report

Qualifier:

according to guideline

Guideline:

OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)

Principles of method if other than guideline:

The Partition coefficient n-octanol/water of test chemical has been determined by the Reverse Phase High performance Liquid Chromatographic Method according to OECDS guidelines for testing of chemicals ,Method No.117

GLP compliance:

not specified

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Analytical method:

high-performance liquid chromatography

Key result

Type:

log Pow

Partition coefficient:

4

Temp.:

24 °C

Remarks on result:

other: Other details not known

Conclusions:

The Partition coefficient n-octanol/water of test chemical has been determined by the Reverse Phase High performance Liquid Chromatographic Method according to OECDS guidelines for testing of chemicals ,Method No.117 the Log kow value was determined to be 4.0.

Executive summary:

The Partition coefficient n-octanol/water of test chemical has been determined by the Reverse Phase High performance Liquid Chromatographic Method according to OECD guidelines for testing of chemicals, Method No.117 the Log kow value was determined to be 4.0 at 24°C.

Description of key information

The Partition coefficient n-octanol/water of test chemical has been determined by the Reverse Phase High performance Liquid Chromatographic Method according to OECD guidelines for testing of chemicals, Method No.117 the Log kow value was determined to be 4.0 at 24°C.

Key value for chemical safety assessment

Log Kow (Log Pow):

4

at the temperature of:

24 °C

Additional information

In a key study from experimental study report, the Partition coefficient n-octanol/water of test chemical has been determined by the Reverse Phase High performance Liquid Chromatographic Method according to OECD guidelines for testing of chemicals, Method No.117 the Log kow value was determined to be 4.0 at 24°C.

In a supporting study, the Partition coefficient (Pow) of test chemical at 25°C was determined according to the OECD Guideline No. 107,”Shake Flask Method”. In this method the different volumes of a stock solution (n-octanol pre saturated with water) were shaken with different volume of water pre saturated with n-octanol. After centrifugation, both the aqueous phase and octanol phase were analysed by HPLC. The partition coefficient were calculated, from the measured concentration of test chemical in the organic and aqueous phases.The log Pow value was determined to be 3.802± 0.001 at 25°C temperature.