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EC number: 927-957-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: Knudsen cell
- Specific details on test material used for the study:
- Batch No.: WD0066442; EINECS-No.: 927-957-5; Purity: 100 % (UVCB); Appearance: amber liquid; Homogeneity: homogeneous; Molecular weight: 400 - 10000 g/mol
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: 400 g/mol - lowest molecular mass present in the UVCB sub.
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: 400 g/mol - lowest molecular mass present in the UVCB sub.
- Key result
- Test no.:
- #3
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: 3000 g/mol - av. molecular mass based on different constituents
- Key result
- Test no.:
- #4
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: 3000 g/mol - av. molecular mass based on different constituents
- Conclusions:
- Under the study conditions, the vapour pressures at 20 °C and at 25 °C were calculated from the regression equation. For the molecular mass of 400 g/mol the vapour pressure was established at 5.93-E5 Pa (20 °C) and at 9.00-E5 Pa (25 °C). For the molecular mass of 3000 g/mol the vapour pressure was established at 2.16-E5 Pa (20 °C) and at 3.29-E5 Pa (25 °C).
- Executive summary:
A study was conducted to determine the vapour pressure of the test substance according to OECD Guideline 104 and EU Method A.4 using the effusion method (Knudsen Cell), in compliance with GLP. Two different molecular mass (400 and 3000 g/mol) were used for calculation. The vapour pressure of the test substance was determined at seven different temperatures (30, 45, 60, 75, 90, 105 and 120 °C). Experiment 1-3 (nominal temperature 30, 45 and 60 °C) showed no reproducible weight loss. When visible contaminations, caused by explosive evaporation of the test substance, were observed, the cells were meticulously cleaned and weighed. This weight was used as initial weight for the subsequent measurements. To avoid bias, these measurements were not used for calculations. Four experiments could be evaluated as they showed relevant and reproducible weight loss. All evaluated experiments showed good reproducibility, giving relative standard deviations of less than 23 % (limit value from the guideline 30 %) and good correlation. Therefore, the result of the test can be considered valid. For the calculation a molecular mass of 400 and 3000 g/mol was used. 400 g/mol represents the worst case calculation (lowest molecular mass of the UVCB substance), 3000 g/mol represents the average molecular mass based of the different constituents obtained in GPC and LC/MS analysis. Under the study conditions, the vapour pressures at 20 °C and at 25 °C were calculated from the regression equation. For the molecular mass of 400 g/mol the vapour pressure was established at 5.93-E5 Pa (20 °C) and at 9.00-E5 Pa (25 °C). For the molecular mass of 3000 g/mol the vapour pressure was established at 2.16-E5 Pa (20 °C) and at 3.29-E5 Pa (25 °C) (Muckle, 2018).
Reference
The following vapour pressures were determined experimentally and considered as valid
Vapour Pressures (Effusion Method) molecular mass 400 g/mol:
Experiment |
T |
Mean p |
Stand. Dev. p |
RSD p |
No. |
K |
Pa |
Pa |
% |
4 |
348.2 |
3.09E-03 |
7.00E-04 |
22.6% |
5 |
363.2 |
6.21E-03 |
1.20E-03 |
19.3% |
6 |
378.2 |
2.10E-02 |
9.95E-04 |
4.7% |
7 |
393.2 |
2.94E-02 |
5.88E-03 |
20.0% |
Stand. Dev. = Standard Deviation; RSD = Relative Standard Deviation
Vapour Pressures (Effusion Method) molecular mass 3000 g/mol:
Experiment |
T |
Mean p |
Stand. Dev. p |
RSD p |
No. |
K |
Pa |
Pa |
% |
4 |
348.2 |
1.13E-03 |
2.55E-04 |
22.6% |
5 |
363.2 |
2.27E-03 |
4.38E-04 |
19.3% |
6 |
378.2 |
7.65E-03 |
3.63E-04 |
4.7% |
7 |
393.2 |
1.08E-02 |
2.15E-03 |
20.0% |
Both graphs 1/T vs. log (p) show a straight line with a correlation coefficient of –0.9830.
Description of key information
The vapour pressure was determined according to OECD Guideline 104 and EU Method A.4 (Muckle, 2018).
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
Molecular mass 400 g/mol (lowest MW present in the UVCB substance):
Vp at 20 °C: 5.93-E5 Pa
Vp at 25 °C: 9.00-E5 Pa
Molecular mass 3000 g/mol (av. MW based of the different constituents):
Vp at 20 °C: 2.16-E5 Pa
Vp at 25 °C: 3.29-E5 Pa
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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