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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
![](https://echa.europa.eu/o/diss-blank-theme/images/factsheets/A-REACH/factsheet/print_physical-and-chemical-properties.png)
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 02/12/2008 to 17/02/2009
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study conducted to GLP in accordance with recognised guideline, but involving an estimation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 009
- Report date:
- 2009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- yes
- Remarks:
- (see below)
- Principles of method if other than guideline:
- The standard A6 Method was not applicable to this test material due to highly viscous samples being produced at high concentration levels. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guideline. Thus, the water solubility was estimated on visual inspection.
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- 20.1 - 22 other: % w/w
- Temp.:
- 20 °C
- pH:
- 7.2 - 7.3
- Details on results:
- It is evident from the information obtained in the hydrolysis study and data relating to the pH of the test material in water that negligible hydrolysis of the sample solution occurred during the course of the water solubility test.
The standard A6 Method was not applicable to this test material due to highly viscous samples being produced at high concentration levels. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guideline. Thus, the water solubility was estimated based on visual inspection.
The small dots of material noted in some samples were considered to be due to impurities, as increasing the test material concentration did not significantly affect the appearance of the samples.
Any other information on results incl. tables
The water solubility of the test material has been determined to be in the range 20.1 to 22.0 % w/w of solution at 20.0 ± 0.5°C.
Observations, concentrations and pH's relating to the samples are shown in the following table:
Sample |
Concentration (% w/w) |
Observations |
pH |
1 |
16.1 |
Dark blue solution. Small dots of undissolved test material on the bottom and sides of the vessel. |
7.2 |
2 |
18.6 |
Dark blue solution. Small dots of undissolved test material on the bottom and sides of the vessel. |
7.2 |
3 |
20.1 |
Dark blue solution. Small dots of undissolved test material on the bottom and sides of the vessel. |
7.2 |
4 |
22.0 |
Dark blue solution with excess test material. Sample is more viscous than Samples 1 to 3. |
7.2 |
5 |
24.0 |
Dark blue solution with excess test material. Sample is more viscous than Samples 1 to 3. |
7.2 |
6 |
26.0 |
Dark blue solution with excess test material. Sample is more viscous than Samples 1 to 3. |
7.3 |
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of the test material has been determined to be in the range 20.1 to 22.0 % w/w of solution at 20.0 ± 0.5°C.
It is evident from the information obtained in the hydrolysis study and data relating to the pH of the test material in water that negligible hydrolysis of the sample solution occurred during the course of the water solubility test.
The standard A6 Method was not applicable to this test material due to highly viscous samples being produced at high concentration levels. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guideline. Thus, the water solubility was estimated based on visual inspection.
The small dots of material noted in some samples were considered to be due to impurities, as increasing the test material concentration did not significantly affect the appearance of the samples. - Executive summary:
In a determination of general physico-chemical properties study (Harlan project number: 0959/0224) the test material has been determined to be in the range 20.1 to 22.0 % w/w of solution at 20.0 ± 0.5°C.
The determination was carried out using a procedure based on the flask method, Method A6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008.
It is evident from the information obtained in the hydrolysis study and data relating to the pH of the test material in water that negligible hydrolysis of the sample solution occurred during the course of the water solubility test.
The standard A6 Method was not applicable to this test material due to highly viscous samples being produced at high concentration levels. It was therefore not possible to prepare samples at five times the saturation level as recommended in the guideline. Thus, the water solubility was estimated based on visual inspection.
The small dots of material noted in some samples were considered to be due to impurities, as increasing the test material concentration did not significantly affect the appearance of the samples.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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