Registration Dossier
Registration Dossier
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EC number: 471-480-0 | CAS number: 1645-83-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: Method for testing partition coefficient by Japanese Ministry of Environment
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.6
- Temp.:
- 25 °C
- pH:
- 7
- Details on results:
- All reference standards had measured log kow values that were expected
- Conclusions:
- The substance has a log Kow of 1.6.
- Executive summary:
The partitioning coefficient octanol-water (Kow) of the substance was determined in a study in accordance with OECD TG 117 (HPLC method) and in compliance with GLP criteria (Kurume Laboratory, 2008). From the results, a log Kow of 1.6 was determined for the test substance.
Reference
Description of key information
A log Kow of 1.6 was determined for the test substance.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.6
- at the temperature of:
- 25 °C
Additional information
In the key study, the HPLC method was used to determine the Log Kow of 1.6. The supporting study presents an estimated log Kow value of 2.01 according to KOWWIN 1.67.
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