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EC number: 421-090-1 | CAS number: 131298-44-7 Isodecyl benzoate
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
Acute Oral Toxicity Study of Isodecyl Benzoate in Rats; GLP conducted study following EPA Guideline 81-1 (1982).
A 14 day acute oral gavage rat toxicity study was conducted using five male rats and five female rats. The estimated oral LD50 for both males and females is >5.0 g/kg of body weight.
Acute Dermal Toxicity Study of Isodecyl Benzoate in Rats; GLP run study following Guideline EPA OPP 81-2 (1987).
The estimated dermal LD50 for Isodecyl Benzoate in male and female rabbits is > 2.0 g/kg of body weight.
An Acute (4-hour) inhalation Toxicity Study in the Rat via Nose-Only Exposure Toxicity Study with Isodecyl Benzoate in the Rat: Acute Toxic Class (ATC) Method; GLP conducted study conducted according to OECD Guideline 436 (2007). Average gravimetric exposure concentration of 5.5 mg/L (milligrams of test substance/Liter of air) with a range of 5.2 – 5.7 mg/L. A total of 124.1 grams of test substance was used during the exposure, resulting in a nominal concentration of 23 mg/L. Highly respirable particle size distribution measurements were an average mass median aerodynamic diameter of 2.41 µm with an average geometric standard deviation of 2.12 and 12% of particles ≤ 1.0 µm, 75% of particles ≤ 4.0 µm and 97% of particles ≤ 10 µm.
The acute inhalation LC50 in rats is > 5.5 mg/L.
Justification for classification or non-classification
The estimated oral LD50 for both males and females is >5.0 g/kg of body weight.
The estimated dermal LD50 for Isodecyl Benzoate in male and female rabbits is > 2.0 g/kg of body weight.
Isodecyl benzoate was practically non-toxic by inhalation to rats by nose-only inhalation exposure with a 4 -hour LC 50 greated than 5.5 mg/L (mean gravimetric exposure concentration) for males and females and therefore does not require classification.
No classification for acute toxicity is indicated according to the general classification and labeling requirements for dangerous substances and preparations (Directive 67-548-EEC) or the classification, labeling and packaging (CLP) regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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