Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 287-477-0 | CAS number: 85535-85-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a guinea pig maximisation test, a group of 20 animals were induced by an intradermal injection of 20% Chloroparaffin 40G (a C14-17 chlorinated paraffin; 40% chlorination, containing 1% epoxy stabilizer) and a subsequent topical application of the undiluted test material. At topical induction, the undiluted material produced "an intense, sometimes haemorrhagic, purulent inflammation", most likely associated with pre-treatment with Freund's Adjuvant. The initial challenge was with undiluted material and the second challenge with a 50% solution in maize oil. Following initial challenge, one test and one control animal produced a reaction at 48 h, with a score of 1 and 3 respectively. No skin response was seen after the second challenge (Murmann, 1988). In addition, no skin sensitisation reactions were seen in two other guinea pig maximisation tests conducted with Meflex DC024 and Meflex DC029 (C14-17 chlorinated paraffins; 40-45% chlorination respectively, containing 0.2% epoxy stabiliser) (Chater, 1978).
No data are available on skin sensitisation potential in humans. Overall, the available data on MCCPs and the generally unreactive nature of MCCPs (and data on SCCPs) indicate an absence of skin sensitisation potential.
Migrated from Short description of key information:
No evidence of a skin sensitisation potential was reported in three guinea pig maximisation tests using diluted C14-17 chlorinated paraffins (40 or 45% chlorination, containing 0.2 or 1% epoxy stabiliser).
Respiratory sensitisation
Endpoint conclusion
- Additional information:
Not expected to be respiratory sensitisers.
Migrated from Short description of key information:
There are no data relating to respiratory sensitisation in humans or laboratory animals. However, the generally unreactive nature of this group of substances and the lack of skin sensitisation potential suggests that they do not possess the potential to cause such an effect.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.