Registration Dossier
Registration Dossier
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EC number: 278-355-8 | CAS number: 75980-60-8
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Municipal activated sludge from laboratory wastewater treatment plants fed with municipal sewage.
- Concentration of sludge: 30 mg/l - Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: 240 ml inorganic medium, 10 mL inoculum, 100 mg/L test substance
- Test temperature: room temperature
- pH: 7.3 - 7.7
- pH adjusted: no
TEST SYSTEM
- Culturing apparatus: Sapromat
- Number of culture flasks/concentration: 7
SAMPLING
- Sampling frequency: daily
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes
- Abiotic sterile control: yes
- Toxicity control: yes - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0 - 10
- Sampling time:
- 28 d
- Details on results:
- Kinetic of control substance (in %):
= 70 - 80 after 14 day(s) - Interpretation of results:
- other: The test substance is poorly biodegradable and not readily biodegradable according to OECD criteria.
Reference
Description of key information
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
The substance was found to be not readily biodegradable in a standard OECD 301F respirometric test. At a test concentration of 100 mg/L the biodegradation degree (BOD of ThOD) was 0 – 10%.
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