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EC number: 245-018-1 | CAS number: 22464-99-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Guideline study with acceptable restrictions (e.g. non-GLP; instead of secondary effluent as recommended by the guideline, the primary effluent of a municipal sewage treatment plant was used as inoculum for this study. The authors justified this by referring (1) to the microbial concentration in the secondary effluent that was too low for the purpose of the study, and (2) to the possible presence of chemical residues within the secondary effluent that may interfere with the biological activity.)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- sewage, domestic (adaptation not specified)
- Details on inoculum:
- INOCULUM :
- Target concentration of microbes in test solution (OECD 301 E): 10E+05 cells/L
- Origin of the inoculum : Municipal sewage treatment plant , Suomenoja , Espoo 26.05.1998
Concentration of inoculum : 1. Secondary effluent approx. 10E+03 - 10E+04 cells/ml; 2. Primary effluent approx. 10E+06 cells/ml
(Easycult TTC, Orion Diagnostica ); Inoculum 2. was used in the test to obtain sufficient microbe concentration
- Preparation of inoculum : Filtration (Schleicher & Schuell 5891 Black ribbon )
- Addition into test solution : 0.5 ml/I - Duration of test (contact time):
- 28 d
- Initial conc.:
- 20 mg/L
- Based on:
- DOC
- Parameter followed for biodegradation estimation:
- DOC removal
- Details on study design:
- TEST CONDITIONS : Incubation shaker New Brunswick G25-KLC
Continuous shaking 120 rp m
Temperature 22 ± 2 °C
Dark
Test vessels 2 I conical flasks , volume of the test solution at start 1000 ml
Free exchange of air in test vessel s
SAMPLING: DOC-samples 50 ml/sampling time and flask
Filtration of samples with Gelman Ion chromatography Acrodisc 0 .45 pm
Storage of filtered samples in -20 °C before analysis
test series:
inoculum blank (inoculum + mineral medium),
test substance (inoculum + mineral medium + test substance),
reference substance (inoculum + mineral medium + reference substance),
toxicity test (inoculum + mineral medium + test substance + reference substance) - start conditions:
mineral medium: pH 7.6, 9 mg/l O2 (= 100 %),
test substance solution: pH 7.45 - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (DOC removal)
- Value:
- 99
- Sampling time:
- 28 d
- Parameter:
- % degradation (DOC removal)
- Value:
- 90.1
- Sampling time:
- 7 d
- Details on results:
- RS-Freetext:
Biodegradation (% relate to DOC)
0 d 2 d 5 d 7 d 14 d 28 d
test substance
(mean) 0 67.2 91.4 90.7 94.9 99.2
reference
substance 0 83.8 97.8 95.6 96.8 99.3
toxicity test 0 76.1 98.2
Biodegradation 10 d window
10 % 70 %
test substance 0.3 d 2.3 d 0.3 d - 10.3 d
reference
substance 0.2 d 1.7 d 0.2 d - 10.2 d
Conclusion:
2-ethylhexanoic acid is readily biodegradable:
- biodegradation (28 d) > 70 %
- Pass level reached in 10-d window.
Kinetic of test substance (in %):
= 67 after 2 day(s)
= 91 after 5 day(s)
= 91 after 7 day(s)
= 95 after 14 day(s)
Kinetic of control substance (in %):
= 84 after 2 day(s)
= 98 after 5 day(s)
Degradation products: not measured - Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Reference
Abiotic and adsorption tests were poisoned with 15 mg/l Na azide to prevent bioactivity. The dosage was not sufficient to stop microbial growth in test vessels, and so the tests were interrupted as the preliminary results showed at the same time that these factors are not likely to interfere the biodegradation of the test substance.
test has been performed by Ekolab Environmental Oy (sponsor: Finnish Chemicals Oy)
Description of key information
2-ethylhexanoic acid is readily biodegradable (according to OECD criteria).
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
As key study regarding biodegradability of 2-ethylhexanoic acid a test performed by Ekolab Environmental Oy on behalf of Finnish Chemical Oy (1998) was identified. The test was enforced according to OECD guideline 301E using primary effluent of municipal sewage treatment plant. After 28 days a DOC removal of 99% was measured.
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