Registration Dossier
Registration Dossier
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EC number: 244-311-1 | CAS number: 21282-97-3
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis:
A Hydrolysis study was performed in year 1996 according to OECD Guideline 111 and GLP. The half life of test substance at 50°C for the pH 7 buffer test system was estimated to be 49 hours. The half life of the test substance at 60°C, 70°C and 80°C was estimated to be 10, 4 and 3 hours, respectively. The half life at 25°C was estimated to be 156 hours using the Test 3, pH 7 data.
Ready biodegradation:
A ready biodegradation study was performed in year 1999 according to OECD Guideline No. 301D and EU Method C.4 -E and GLP. The test item did not reach the pass level of 60 % within two weeks. Therefore, the test item was considered to have exceeded the ready biodegradability pass level of 60 % ThODNH3 removal within 28 days, but the 14 day window criterium was not met. The test substance can therefore not in the strict sense be classified as readily biodegradable in this test. However, it may be characterized as inherently and ultimately degradable on the basis of these test results.
Biotic degradation:
According to Annex IX section 9.2.1.4 and 9.2.1.3 of Regulation No. 1907/2006 “Further biotic degradation testing shall be proposed by the registrant if the chemical safety assessment according to Annex I indicated the need to investigate further the degradation of the substance and its degradation products”. The test substance entering the water is not likely to sorb onto suspended solids and sediment based upon the estimated Koc of 30.71 L/kg (based on log Kow, using the EIPSUITE-software). Furthermore, the soil adsorption/desorption properties of the test substance were studied following OECD Test Guideline No. 106 (batch equilibrium method) Koc mean value for soil I is 58.8. Therefore, direct and indirect exposure of sediment and of soil is unlikely. No further testing for these endpoints is proposed.
Bioaccumulation:
The substance does not have the potential to bioaccumulate. In a study according to EU Method A.8, OECD Guideline 107 (Partition Coefficient (n-octanol / water), shake-flask Method) the octanol-water partition coefficient was determined to be logPow = 0.9 at 25°C measured with GC/FID.
Adsorption/desorption:
A adsorption/desorption study was performed in year 1996 according to OECD Guideline 106 (batch equilibrium method) and GLP.
The test substance adsorbed onto the Spodosol, Alfisol and Entisol soils with mean adsorption weight/weight percent values of 21.4, 27.4, and 22.4 %, respectively. Therefore, the test substance adsorbed in sufficient quantity to require the desorption test. The mean desorption weight/weight percent values were 16.9, -1.43, and 7.88 %, respectively.
Furthermore, the log Koc was calculated using the EIPSUITE-software. The resulting Koc was 30.71.
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