Registration Dossier
Registration Dossier
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EC number: 236-164-7 | CAS number: 13197-76-7
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 4.58 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.458 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 0.3 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 16.7 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 1.7 µg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.657 µg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
Reliable experimental study data are available for dodecyl(2-hydroxy-3-sulphonatopropyl)dimethylammonium for acute fish toxicity, acute aquatic invertebrate toxicity and algal toxicity. These studies showed a 96 h LC50 value of 55.2 mg/L for freshwater fish (Danio rerio), a 24 h EC50 value of 4.8 mg/L for Daphnia magna, and a 72 h ErC50 value of 4.58 mg/L and a 72 h NOEC value of 0.508 mg/L for algae (Pseudokirchneriella subcapitata). No chronic ecotoxicity data are available for fish or aquatic invertebrates. A reliable OECD 301C ready biodegradability study is available for dodecyl(2-hydroxy-3-sulphonatopropyl)dimethylammonium which demonstrated that although the substance cannot be considered readily biodegradable (given that complete mineralisation was not achieved), the substance can be considered rapidly biodegradable.
The most conservative acute ecotoxicity data is the 72 h ErC50 value of 4.58 mg/L from the algal toxicity study. Therefore, it is concluded that dodecyl(2-hydroxy-3-sulphonatopropyl)dimethylammonium is ‘Not classified’ for acute aquatic hazard classification under the CLP regulation (Regulation (EC) No 1272/2008), whereas under the Globally Harmonised System (GHS) the substance would be classified as Aquatic Acute Category 2 (H401: Toxic to aquatic life).
The most conservative chronic ecotoxicity endpoint is the 72 h NOEC value of 0.508 mg/L from the algal toxicity study. Given that, as mentioned above, the substance is concluded to be rapidly biodegradable, dodecyl(2-hydroxy-3-sulphonatopropyl)dimethylammonium is classified as Aquatic Chronic Category 3 (H412: Harmful to aquatic life with long lasting effects) under CLP and GHS.
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