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Diss Factsheets
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EC number: 227-114-5 | CAS number: 5661-03-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: All tests were made in accordance with the 'revised OECD Principes of Good Laboratory Practices', Guidelines OECD, Directive 2004/10/EC and Chemikaliengesetz of federal republic of Germany.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Octahydrocyclopenta[c]pyrrole
- EC Number:
- 227-114-5
- EC Name:
- Octahydrocyclopenta[c]pyrrole
- Cas Number:
- 5661-03-0
- Molecular formula:
- C7H13N
- IUPAC Name:
- octahydrocyclopenta[c]pyrrole
- Test material form:
- other: liquid
- Details on test material:
- Colourless liquid, stable, soluble in water, stored at room temperature.
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- Activated sludge from biologic sewage treatment plant was used. The chosen plant is treating mostly domestic sewage.
The sludge was taken from the activation basin of the ESn (Stadtensorgnung Neustadt) sewage treatment plant, im Altenschemel. Batch n°20100305
date of collection : 05 march 2010.
The sludge was filtrated, washed with tap water, twice, then washed with and resuspended in the test medium. It was then aerated for >12hours. The dry matter was determined with 3880mg suspended solids/liter.
All flasks containing medium and inoculum were aerated for 72 hours, CO2-free, moistened air to purge the system of CO2. - Duration of test (contact time):
- 28 d
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
Results and discussion
Any other information on results incl. tables
All validity parameters and values are presented in the following table :
parameter | criterion | found | assessment |
IC content of test item solution in medium | =<5% of TC | <1% | valid |
CO2 emitted by the controls | <70mg/L | 9.8 mg/L | valid |
difference within replicates | =<20% | 4.3% | valid |
degradation of positive control > 60% | <14 days | 9 days | valid |
degradation in the toxicity flask on day 14 | >25% | 33% | valid |
Degradation behaviour of positive control an toxicity control was normal. Abiotic degradation was not observed. Both replicates of the test item showed very good correspondence. No sign of degradation were visible.
All validity criteria were met. Degradation behaviour of positive control an toxicity control was normal. Abiotic degradation was not observed. Both replicates of the test item showed very good correspondence. No sign of degradation were visible.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: NOT READILY BIODEGRADABLE
- Conclusions:
- The degree of biodegradation reached 7.3% after 28 days.
No 10-days window could be identified and the pass level of 60% given in the OECD guideline was missed.
No abiotic degradation was observed.
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