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Diss Factsheets
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EC number: 213-607-2 | CAS number: 993-13-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption, other
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Study period:
- 06th February 2013
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other:
- Version / remarks:
- Using KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency, the adsorption coefficient of the test item was estimated (MCI method and Kow method).
- Qualifier:
- according to guideline
- Guideline:
- other:
- Version / remarks:
- P. J. McCall, D. A. Laskowski, R. L. Swann and H. J. Dishburger “Measurement of Sorption Coefficients of Organic Chemicals and Their Use in Environmental Fate Analysis”; 1981; Assoc. of Off. Anal. Chem., Arlington, VA; p 89 – 109.
- Principles of method if other than guideline:
- The adsorption coefficient of methylphosphonic acid 70 % was estimated using a computer-based atom fragment contribution method, KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency.
- GLP compliance:
- no
- Type of method:
- other: QSAR
- Test temperature:
- not reported
- Details on study design: HPLC method:
- n/a
- Details on sampling:
- n/a
- Details on matrix:
- n/a
- Details on test conditions:
- n/a
- Computational methods:
- Using KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency, the adsorption coefficient of the test item was estimated (MCI method and Kow method).
- Type:
- Koc
- Value:
- 1.41
- Remarks on result:
- other: Calculation (MCI method)
- Type:
- log Koc
- Value:
- 0.148
- Remarks on result:
- other: Calculation (MCI method)
- Type:
- Koc
- Value:
- 7.53
- Remarks on result:
- other: Calculation (Kow method)
- Type:
- log Koc
- Value:
- -0.1
- Remarks on result:
- other: Calculation (Kow method)
- Details on results (HPLC method):
- n/a
- Adsorption and desorption constants:
- n/a
- Recovery of test material:
- n/a
- Concentration of test substance at end of adsorption equilibration period:
- n/a
- Concentration of test substance at end of desorption equilibration period:
- n/a
- Details on results (Batch equilibrium method):
- n/a
- Statistics:
- n/a
- Validity criteria fulfilled:
- yes
- Conclusions:
- Using KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency, the adsorption coefficient of the test item was estimated to be 1.41 (MCI method) and 7.53 x 10-2 (Kow method), log10 Koc 0.148 (MCI method) and -1.12 (Kow method). These values indicate that the test item will have a very high environmental mobility. However, it is anticipated that partitioning forces with the organic carbon content of soils and sediments may not be the dominant force controlling the mobility of the test item in the environment. Strong ionic interaction with clay particles, for example, will also influence the fate of the test item in the environment.
- Executive summary:
Practical testing according to Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001 was not possible due to the strong acidity of the test item. Test guidance indicates that OECD 121 is not applicable to strong acids. Therefore, the adsorption coefficient of Methyl phosphonic acid 70 % was estimated using a computer-based atom fragment contribution method, KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency. Using KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency, the adsorption coefficient (Koc) was estimated to be 1.41 (MCI method) and 7.53 x 10-2 (Kow method), log10 Koc 0.148 (MCI method) and -1.12 (Kow method). The test item was evaluated as the mono-sodium salt, to ensure that it was evaluated at an environmentally relevant pH. These calculated values indicate that the test item will have a very high environmental mobility *. However, it is anticipated that partitioning forces with the organic carbon content of soils and sediments may not be the dominant force controlling the mobility of the test item in the environment. Strong ionic interaction with clay particles, for example, will also influence the fate of the test item in the environment.
* According to P. J. McCall, D. A. Laskowski, R. L. Swann and H. J. Dishburger “Measurement of Sorption Coefficients of Organic Chemicals and Their Use in Environmental Fate Analysis”; 1981; Assoc. of Off. Anal. Chem., Arlington, VA; p 89 – 109.
Reference
Description of key information
Using KOCWIN the adsorption coefficient of the test item was estimated to be 1.41 (MCI method) and 7.53 x 10-2 (Kow method). These values indicate that the test item will have a very high environmental mobility. However, it is anticipated that partitioning forces with the organic carbon content of soils and sediments may not be the dominant force controlling the mobility of the test item in the environment. Strong ionic interaction with clay particles, for example, will also influence the fate of the test item in the environment.
Key value for chemical safety assessment
- Koc at 20 °C:
- 1.41
Additional information
Practical testing according to Method 121 of the OECD Guidelines for Testing of Chemicals, 22 January 2001 was not possible due to the strong acidity of the test item. Therefore, the adsorption coefficient of methylphosphonic acid 70 % was estimated using a computer-based atom fragment contribution method, KOCWIN, version 2.00, © 2000-2008 U.S. Environmental Protection Agency. The adsorption coefficient (Koc) was estimated to be 1.41 (MCI method) and 7.53 x 10-2 (Kow method), log10 Koc 0.148 (MCI method) and -1.12 (Kow method). These calculated values indicate that the test item will have a very high environmental mobility (McCall 1981). However, it is anticipated that partitioning forces with the organic carbon content of soils and sediments may not be the dominant force controlling the mobility of the test item in the environment. Strong ionic interaction with clay particles, for example, will also influence the fate of the test item in the environment.
* P. J. McCall, D. A. Laskowski, R. L. Swann and H. J. Dishburger “Measurement of Sorption Coefficients of Organic Chemicals and Their Use in Environmental Fate Analysis”; 1981; Assoc. of Off. Anal. Chem., Arlington, VA; p 89 – 109.
[LogKoc: 0.148]
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