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EC number: 210-793-7 | CAS number: 623-43-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH
The registration substance consist of the relevant structural elements short chain unsaturated aliphatic and carboxylic ester.
The analogues acrylic acid methyl ester and Ethylhexyl hydrogen maleate have the same structural elements.
Therefore it is considered, that the biodegradation properties of the registration substance are fully comparable to the analogues.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
See test material in this endpont (source) and target chemicals studies.
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 1 (reliable without restriction)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 310 (Ready Biodegradability - CO2 in Sealed Vessels (Headspace Test)
- GLP compliance:
- yes
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Parameter:
- other: TIC/ThIC
- Value:
- 99 - 100
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Reason / purpose for cross-reference:
- read-across source
Reference
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- other: EEC Directive 79-831, Annex V, Part C: Methods for the Determination of Ecotoxicology; Degradation - Biotic Degradation; Manometric Respirometry.
- Version / remarks:
- Bruessel 1984
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Activated sludge from a laboratory wastewater treatment plant, which is operated with municipal wastewater.
- Concentration of the suspended substances at the beginning of the test: 30 mg/L - Duration of test (contact time):
- 28 d
- Initial conc.:
- 103 mg/L
- Based on:
- test mat.
- Initial conc.:
- 632 mg/L
- Based on:
- TOC
- Details on study design:
- TEST SYSTEM
- Culturing apparatus: Sapromat with 7 parallel test tubes. Test volume 2015 mL
CONTROL AND BLANK SYSTEM
- Inoculum blank: Yes, containing only inoculum
- Procedure control: Yes, containing reference compound and inoculum
- Abiotic sterile control: Yes, containing test substance and sterilising agent (HgCl2)
- Toxicity control: Yes, containing test substance, reference compound and inoculum - Reference substance:
- aniline
- Test performance:
- In the respirometric test, the biodegradability of an organic substance in a static, aqueous system with activated sludge of a municipal sewage treatment plant as an inoculum is tested. The biochemical oxygen demand (BOD) in the respirometer is measured and compared with the theoretical oxygen demand (ThOD) and the measured chemical oxygen demand (COD) of the test substance.
- Key result
- Parameter:
- other: % degradation (ThOD)
- Value:
- > 60
- Sampling time:
- 28 d
- Remarks on result:
- other: BOD/ThOD (%) = 70%; BSB/CSB (%) = 65%
- Details on results:
- - Mean duration of lag-phase: 5 days
- Mean duration of degradation phase: 18 days - Results with reference substance:
- - BOD*100 /THOD= 62 %
- Interpretation of results:
- readily biodegradable
- Conclusions:
- Under the conditions of this test the test substance is readily biodegradable as the pass level of >60% degradation was reached within the 28 days period of the study.
- Executive summary:
The ready biodegradability of the test item was assessed over a 28 day period in a study equivalent to OECD guideline 301 C (BASF, 1989). The test item was tested at a concentration of 103 mg/L, corresponding to total organic carbon (TOC) of 632 mg/g. The test item was exposed to an aqueous system of activated sludge of a municipal sewage treatment plant as an inoculum for 28 days. The biodegradation was followed by the oxygen uptake (biological oxygen demand, BOD) during exposure. Aniline was tested as a reference substance and showed a degradation of 62% after 28 days. Under the conditions of this test the test substance is readily biodegradable as the pass level of >60% degradation was reached within the 28 days period of the study.
10 -day-window: yes
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.