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EC number: 202-974-4 | CAS number: 101-77-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to terrestrial arthropods: long-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 232 (Collembolan Reproduction Test in Soil)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- yes
- Vehicle:
- yes
- Details on preparation and application of test substrate:
- The stock solution was prepared in ethanol. An appropriate amount of the stock and the dosage solutions respectively was used to soak a
portion of the quartz sand of the artificial soil. After evaporation of the solvent by placing under a fume hood, the quartz sand was coated by the test item. - Test organisms (species):
- Folsomia candida
- Animal group:
- Collembola (soil-dwelling springtail)
- Details on test organisms:
- - Age of the test organisms; Juvenile with an age of 10 – 12 days
- Study type:
- laboratory study
- Limit test:
- no
- Total exposure duration:
- 28 d
- Test temperature:
- 20 ± 2 ºC
- pH (if soil or dung study):
- artificial soil adjusted to pH 6 ± 0.5
- Humidity:
- 40 – 60% of WHCmax
- Photoperiod and lighting:
- 16 : 8 h light/dark with a constant light intensity at the substrate surface of 400 – 800 Lx
- Details on test conditions:
- Artificial soil consists of:
- 5% Sphagnum peat (no visible plant remains; finely ground and air-dried)
- 20% Kaolin-Clay (kaolinite content > 30%)
- approximately 74% Quartz sand (fine sand content with particles between 50 and
200 μm higher than 50%)
- <1% Calcium carbonate (CaCO3) - Nominal and measured concentrations:
- Nominal: 56.2, 100, 178, 316, 5062 and 1000 mg test item/kg soil (dw).
Plus a solvent control and dionised water control.
Number of replicates: 4 treatment and 4 deionised water controls; 8 solvent controls containing 10
collembolans each.
The concenration of the stock solution, used as application solution for the highest test concentration was analytically verified in duplicate. The recovery ranged from 100.00.to 100.75 % of the nominal concentration. - Reference substance (positive control):
- yes
- Remarks:
- boric acid
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 562 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 28 d
- Dose descriptor:
- EC50
- Effect conc.:
- 909.9 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Reference
Description of key information
In experimental studies with Folsomia candida an EC50 (28 d) of 909.9 mg/kg dw was determined.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil dwelling arthropods:
- 909.9 mg/kg soil dw
- Long-term EC10, LC10 or NOEC for soil dwelling arthropods:
- 562 mg/kg soil dw
Additional information
In an experimental study according to the OECD Guideline 232 and GLP regulations the toxicity to terrestrial arthropods was assessed. The springtail Folsomia candida was exposed to the test item for 28 d in a laboratory study. The effect on reproduction was measured and an EC50 of 909.9 mg/kg soil dw was determined, as well as a NOEC of 562 mg/kg. (ECT, 2011).
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