EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

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Last updated 18 aprīlis 2024. Database contains 4917 unique substances/entries.
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Substance Name
EC No.
CAS No.
EU CLP (1272/2008)
EU REACH: List of SVHC
EU_BA Directive 2000/54/EC
 
2-methyl-4-phenylpentanol
PAMPLEFLEUR
402-770-7
92585-24-5
Skin Sens. 1
Details
2-methyl-5-(1,1,3,3-tetramethylbutyl)hydroquinone
AF-336
400-530-6
723-38-6
Eye Dam. 1; Skin Sens. 1
Details
2-methyl-5-phenylpentanol
ROSAPHEN
405-890-8
25634-93-9
Eye Irrit. 2; Skin Irrit. 2
Details
2-methyl-5-tert-butylthiophenol
438-520-9
7340-90-1
Flam. Liq. 3; Repr. 2; STOT RE 2; Asp. Tox. 1; Eye Irrit. 2; Skin Irrit. 2; Skin Sens. 1; STOT SE 3
Details
2-methyl-m-phenylene diisocyanate; toluene-2,4-di-isocyanate
202-039-0
91-08-7
Carc. 2; Acute Tox. 2; Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Resp. Sens. 1; Skin Sens. 1
Details
2-methyl-m-phenylenediamine; 2,6-toluenediamine
212-513-9
823-40-5
Muta. 2; Acute Tox. 4; Skin Sens. 1
Details
2-methyl-p-phenylenediamine sulphate
228-871-4
6369-59-1
Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
Details
2-methyl-p-phenylenediamine sulphate
210-431-8
615-50-9
Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
Details
2-methyl-p-phenylenediamine; 2,5-toluenediamine
202-442-1
95-70-5
Acute Tox. 3; Acute Tox. 4; Skin Sens. 1
Details
2-methylaminoethanol; N-methylethanolamine; N-methyl-2-ethanolamine; N-methyl-2-amino ethanol; 2-(methylamino)ethanol
203-710-0
109-83-1
Acute Tox. 4; Skin Corr. 1B
Details
2-methylaziridine; propyleneimine
200-878-7
75-55-8
Flam. Liq. 2; Carc. 1B; Acute Tox. 2; Acute Tox. 1; Eye Dam. 1
Details
2-methylbutan-2-ol; tert-pentanol
200-908-9
75-85-4
Flam. Liq. 2; Acute Tox. 4; STOT SE 3; Skin Irrit. 2
Details
2-methylbutyl acetat
210-843-8
624-41-9
Flam. Liq. 3
Details
2-methylbutyl formate
252-343-2
35073-27-9
Flam. Liq. 2; Eye Irrit. 2; STOT SE 3
Details
2-methylbutyl propionate
219-449-0
2438-20-2
Flam. Liq. 3
Details
2-methylcyclohexanol, mixed isomers
209-512-0
583-59-5
Acute Tox. 4
Details
2-methylcyclohexanone
209-513-6
583-60-8
Flam. Liq. 3; Acute Tox. 4
Details
2-methylheptane
209-747-9
592-27-8
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
Details
2-methylhexane
209-730-6
591-76-4
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
Details
2-methylimidazole
211-765-7
693-98-1
Repr. 1B
R Toxic for reproduction (article 57c)
Details
2-methylisothiazol-3(2H)-one
220-239-6
2682-20-4
Acute Tox. 2; Acute Tox. 3; Skin Corr. 1B; Eye Dam. 1; Skin Sens. 1A
Details
2-methylpentane
203-523-4
107-83-5
Flam. Liq. 2; Asp. Tox. 1; Skin Irrit. 2; STOT SE 3
Details
2-methylpentane-2,4-diol
203-489-0
107-41-5
Eye Irrit. 2; Skin Irrit. 2
Details
2-methylpropan-1-ol; iso-butanol
201-148-0
78-83-1
Flam. Liq. 3; STOT SE 3; Skin Irrit. 2; Eye Dam. 1
Details
2-methylpropan-2-ol; tert-butyl alcohol
200-889-7
75-65-0
Flam. Liq. 2; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
Details
2-methylpropene
204-066-3
115-11-7
Flam. Gas 1; Press. Gas
Details
2-methylpropyl (R)-2-hydroxypropanoate
D(+)-LACTATE D'ISOBUTYLE
407-770-0
61597-96-4
Eye Irrit. 2
Details
2-methylpropyl 2-hydroxy-2-methylbut-3-enoate
VINYLMILCHSÄURE-ISO-BUTYLESTER
406-235-9
72531-53-4
Eye Irrit. 2; Skin Irrit. 2
Details
2-methylpyridine; 2-picoline
203-643-7
109-06-8
Flam. Liq. 3; Acute Tox. 4; Eye Irrit. 2; STOT SE 3
Details
2-methylstyrene; 2-vinyltoluene
210-256-7
611-15-4
Acute Tox. 4
Details
2-n-butyl-benzo[d]isothiazol-3-one
SUBSTANCE S123386; VANQUISH 100
420-590-7
4299-07-4
Skin Corr. 1B; Skin Sens. 1
Details
2-n-hexadecylhydroquinone
AF-368
406-400-5
4595-26-0
STOT RE 2; Skin Irrit. 2; Skin Sens. 1
Details
2-naphthol
205-182-7
135-19-3
Acute Tox. 4
Details
2-naphthylamine
202-080-4
91-59-8
Carc. 1A; Acute Tox. 4
Details
2-naphthylamino-6-sulfomethylamide
2-NAPHTHYLAMIN-6-SULFOMETHYLAMID; FAT 92'365/A
412-120-4
104295-55-8
STOT RE 2; Skin Sens. 1
Details
2-Naphthylammonium chloride
210-313-6
612-52-2
Carc. 1A; Acute Tox. 4
Details
2-nitro-2-phenyl-1,3-propanediol
2-NPP
410-360-4
5428-02-4
STOT RE 1; Acute Tox. 4; Skin Sens. 1
Details
2-nitro-p-anisidine; 4-methoxy-2-nitroaniline
202-547-2
96-96-8
Acute Tox. 2; Acute Tox. 1; STOT RE 2
Details
2-nitroanisole
202-052-1
91-23-6
Carc. 1B; Acute Tox. 4
Details
2-nitronaphthalene
209-474-5
581-89-5
Carc. 1B
Details
2-nitropropane
201-209-1
79-46-9
Flam. Liq. 3; Carc. 1B; Acute Tox. 4
Details
2-nitrotoluene
201-853-3
88-72-2
Carc. 1B; Muta. 1B; Repr. 2; Acute Tox. 4
Details
2-phenoxyethanol
204-589-7
122-99-6
Acute Tox. 4; STOT SE 3; Eye Dam. 1
Details
2-phenyl-1,3-propanediol
1,3-PPD
411-810-2
1570-95-2
Eye Dam. 1
Details
2-phenylethylisocyanate
2-PHENYLETHYLISOCYANAT; 2-PHENYLETHYLISOCYANATE; PHENYL ETHYL ISOCYANATE
413-080-0
1943-82-4
Acute Tox. 3; Acute Tox. 4; Skin Corr. 1A; Resp. Sens. 1; Skin Sens. 1
Details
2-phenylhexanenitrile
SALICYNALVA
423-460-8
3508-98-3
Acute Tox. 4
Details
2-phenylphenol (ISO)biphenyl-2-ol; 2-hydroxybiphenyl
201-993-5
90-43-7
Eye Irrit. 2; STOT SE 3; Skin Irrit. 2
Details
2-phenylpropene; α-methylstyrene
202-705-0
98-83-9
Flam. Liq. 3; Eye Irrit. 2; STOT SE 3
Details
2-phenylthioaniline
2-ADPS
413-030-8
1134-94-7
Skin Sens. 1
Details
2-phthalimidoethyl N-[4-(2-cyano-4-nitrophenylazo)phenyl]-N-methyl-β-alaninate
426-400-9
170222-39-6
Skin Sens. 1
Details
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