Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 231-679-3 | CAS number: 7681-82-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to microorganisms, other
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Justification for type of information:
- Data is from secondary literature
- Qualifier:
- according to guideline
- Guideline:
- other: Refer below principle
- Principles of method if other than guideline:
- Study was conducted to determine the effect of test chemical on the growth and cell proliferation of microorganisms Entosiphon sulcatum.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Entosiphon sulcatum
- Details on inoculum:
- Details on test organisms:
Color oser, bacterivorous flagellate cells were used - Test type:
- static
- Water media type:
- other: Wastewater
- Total exposure duration:
- 72 h
- Test temperature:
- 25° C
- pH:
- 6.9
- Nominal and measured concentrations:
- nominal concentration
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 72 h
- Dose descriptor:
- LOEC
- Effect conc.:
- 40 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: cell proliferation inhibition
- Remarks on result:
- other: Other details not known
- Validity criteria fulfilled:
- not specified
- Conclusions:
- After the exposure of test chemical for 72 hrs, with microorganisms Entosiphon sulcatum, the LOEC was observed at 40 mg/l.
- Executive summary:
Study was conducted to determine the effect of test chemical on the growth and cell proliferation of microorganisms Entosiphon sulcatum. Test conducted under the static system at 25° C. After the exposure of test chemical for 72 hrs, with microorganisms Entosiphon sulcatum, the LOEC was observed at 40 mg/l.
Reference
Description of key information
Study was conducted to determine the effect of test chemical on the growth and cell proliferation of microorganisms Entosiphon sulcatum. Test conducted under the static system at 25° C. After the exposure of test chemical for 72 hrs, with microorganisms Entosiphon sulcatum, the LOEC was observed at 40 mg/l.
Key value for chemical safety assessment
Additional information
Various studies available for the test chemical were reviewed to determine the toxic nature of test chemical on the growth and other activity of microorganisms. The studies are as mentioned below:
In the first study toxicity was measured on the basis of cell growth inhibition. Study was conducted to determine the effect of test chemical on the growth and cell proliferation of microorganisms Entosiphon sulcatum. Test conducted under the static system at 25° C. After the exposure of test chemical for 72 hrs, with microorganisms Entosiphon sulcatum, the LOEC was observed at 40 mg/l.
Similarly first study was supported by the second study from secondary source. Study was conducted to evaluate the effect of test chemical on the growth of microorganism Pseudomonas putida. Test conducted for 16 hrs. The low observed effect concentration (LOEC) value observed is 614 mg/l in Pseudomonas putida in a aquatic toxicity study conducted with test chemical on the basis of Cell Proliferation effect. On the basis of LOEC value it is concluded that the test chemical does not exhibit toxicity to microorganism (Pseudomonas putida).
Thus based on the above both studies chemical toxicity was observed as very low and the LOEC ranges from 40-614 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.