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EC number: 437-450-6 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Between 06 December 1999 and 07 December 1999.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
- Deviations:
- not specified
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: vapour pressure balance
- Specific details on test material used for the study:
- No further details specified in the study report.
- Key result
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Conclusions:
- The vapour pressure of APAN has been determined to be 3.3e-8 Pa at 25 °C.
- Executive summary:
The test procedure was based on Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
APAN has been determined to have a vapour pressure of 3.3 x 10-8Pa at 25 °C, using a vapour pressure balance.
Reference
Run 1
Temperature (°C) |
Temperature (K) |
Reciprocal temperature (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10Vp |
129 |
402.15 |
0.002486634 |
42.92 |
4.292E-08 |
0.059583956 |
-1.224870665 |
128 |
401.15 |
0.002492833 |
37.08 |
3.708E-08 |
0.051476540 |
-1.288390653 |
127 |
400.15 |
0.002399063 |
34.04 |
3.404E-08 |
0.047256241 |
-1.325540827 |
126 |
399.15 |
0.002505324 |
33.93 |
3.393E-08 |
0.047103533 |
-1.326946519 |
125 |
398.15 |
0.002511616 |
24.52 |
2.452E-08 |
0.034040042 |
-1.468009913 |
124 |
397.15 |
0.002517940 |
22.43 |
2.243E-08 |
0.031138587 |
-1.506701105 |
123 |
396.15 |
0.002524296 |
21.14 |
2.114E-08 |
0.029347736 |
-1.532425396 |
122 |
396.15 |
0.002530685 |
21.93 |
2.193E-08 |
0.030444458 |
-1.516491747 |
121 |
394.15 |
0.002537105 |
20.84 |
2.084E-08 |
0.028931259 |
-1.538632664 |
120 |
393.15 |
0.002543558 |
17.60 |
1.760E-08 |
0.024433309 |
-1.612017711 |
119 |
392.15 |
0.002550045 |
16.92 |
1.692E-08 |
0.023489295 |
-1.629130020 |
118 |
391.15 |
0.002556564 |
13.78 |
1.378E-08 |
0.019130170 |
-1.718281161 |
117 |
390.15 |
0.002563117 |
11.71 |
1.172E-08 |
0.016270363 |
-1.788602767 |
116 |
389.15 |
0.002569703 |
10.68 |
1.968E-08 |
0.014826576 |
-1.828959126 |
115 |
388.15 |
0.002576324 |
10.09 |
1.009E-08 |
0.014007505 |
-1.853639212 |
114 |
387.15 |
0.002582978 |
8.96 |
8.960E-09 |
0.012438776 |
-1.905222369 |
113 |
386.15 |
0.002589667 |
7.73 |
7.730E-09 |
0.010731220 |
-1.969350885 |
112 |
385.15 |
0.002596391 |
7.11 |
7.110E-09 |
0.009870502 |
-2.005660778 |
111 |
384.15 |
0.002603150 |
7.31 |
7.310E-09 |
0.010148153 |
-1.993613002 |
110 |
383.15 |
0.002609944 |
6.10 |
6.100E-09 |
0.008468363 |
-2.072200544 |
109 |
382.15 |
0.002616774 |
5.81 |
5.819E-09 |
0.008065769 |
-2.093354246 |
108 |
381.15 |
0.002623639 |
5.44 |
5.440E-09 |
0.007552114 |
-2.121931479 |
107 |
380.15 |
0.002630541 |
4.20 |
4.200E-09 |
0.005830676 |
-2.234281088 |
106 |
379.15 |
0.002637479 |
4.10 |
4.100E-09 |
0.005691850 |
-2.244746522 |
105 |
378.15 |
0.002644453 |
3.76 |
3.760E-09 |
0.005219843 |
-2.282342534 |
104 |
377.15 |
0.002651465 |
2.87 |
2.870E-09 |
0.003984295 |
-2.399648482 |
103 |
376.15 |
0.002658514 |
2.46 |
2.460E-09 |
0.003415110 |
-2.466595272 |
102 |
375.15 |
0.002665600 |
2.16 |
2.160E-09 |
0.002998633 |
-2.523976628 |
101 |
374.15 |
0.002672725 |
2.00 |
2.000E-08 |
0.002776512 |
-2.556500383 |
A plot of Log10(vapour Pressure (Pa)) versus reciprocal temperature (1/T(K)) for run 1 give the following statistical data using an unweighted least squares treatment.
Slope -6915.705
Standard deviation in slope 117.242
Intercept 15.692
Standard deviation in intercept 0.302
The results obtained indicate the following vapour pressure relationship.
Log10(Vp (Pa)) = -6.915.705/temp(K) + 15.962
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -7.233.
Run 2
Temperature (°C) |
Temperature (K) |
Reciprocal temperature (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10Vp |
126 |
399.15 |
0.002505324 |
18.54 |
1.854E-08 |
0.002578270 |
-1.589420649 |
127 |
400.15 |
0.002499063 |
21.31 |
2.131E-08 |
0.029583740 |
-1.528946929 |
128 |
401.15 |
0.002492833 |
23.38 |
2.338E-08 |
0.032457430 |
-1.488685872 |
129 |
402.15 |
0.002486634 |
26.01 |
2.601E-08 |
0.036108544 |
-1.442390027 |
130 |
403.15 |
0.002480466 |
29.25 |
2.925E-08 |
0.020606494 |
-1.391404508 |
131 |
404.15 |
0.002474329 |
32.14 |
3.214E-08 |
0.044618554 |
-1.350484506 |
132 |
405.15 |
0.002468222 |
35.27 |
2.527E-08 |
0.048963796 |
-1.310124919 |
133 |
406.15 |
0.002462145 |
38.53 |
3.853E-08 |
0.053489511 |
-1.271731370 |
134 |
407.15 |
0.002456097 |
43.10 |
4.310E-08 |
0.059833842 |
-1.223053109 |
135 |
408.15 |
0.002450080 |
45.86 |
4.586E-08 |
0.063665429 |
-1.196096328 |
136 |
409.15 |
0.002444091 |
48.15 |
4.815E-08 |
0.066844536 |
-1.1749340987 |
137 |
410.15 |
0.002438132 |
54.29 |
5.429E-08 |
0.075368429 |
-1.122810537 |
138 |
411.15 |
0.002432202 |
59.84 |
5.984E-08 |
0.083073251 |
-1.080538794 |
139 |
412.15 |
0.002426301 |
61.51 |
6.151E-08 |
0.085391639 |
-1.068584652 |
140 |
413.15 |
0.002420428 |
66.16 |
6.616E-08 |
0.091847030 |
-1.036934882 |
141 |
414.15 |
0.002414584 |
75.26 |
7.526E-08 |
0.104480162 |
-0.980966165 |
142 |
415.15 |
0.002408768 |
79.28 |
7.928E-08 |
0.110060951 |
-0.958366737 |
143 |
416.15 |
0.002402980 |
85.04 |
8.504E-09 |
0.118057307 |
-0.927907127 |
144 |
417.15 |
0.002397219 |
92.60 |
9.260E-08 |
0.128552524 |
-0.890919392 |
145 |
418.15 |
0.002391486 |
101.64 |
1.016E-07 |
0.141102360 |
-0.850465722 |
146 |
419.15 |
0.002385781 |
107.23 |
1.072E-07 |
0.148862712 |
-0.827214073 |
147 |
420.15 |
0.002380102 |
119.23 |
1.192E-07 |
0.165521787 |
-0.781144835 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 2 gives the following statistical data using an unweighted least squares treatment.
Slop -6211.851
Standard deviation in slope 82.522
Intercept 14.009
Standard deviation in intercept 0.202
The results obtained indicate the following vapour pressure relationship
Log10(Vp (Pa)) = 6211.851/temp(K) + 14.009
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -6.826.
Run 3
Temperature (°C) |
Temperature (K) |
Reciprocal temperature (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10Vp |
130 |
403.15 |
0.002480466 |
14.29 |
1.429E-08 |
0.019838181 |
-1.702498150 |
131 |
404.15 |
0.002474329 |
14.81 |
1.481E-08 |
0.020560074 |
-1.686975320 |
132 |
405.15 |
0.002468222 |
18.04 |
1.804E-08 |
0.025044142 |
-1.601293846 |
133 |
406.15 |
0.002462145 |
18.80 |
1.880E-08 |
0.026099217 |
-1.583372529 |
134 |
407.15 |
0.002456097 |
19.86 |
1.986E-08 |
0.027570768 |
-1.559551135 |
135 |
408.15 |
0.002450080 |
21.71 |
2.171E-08 |
0.030139042 |
-1.520870555 |
136 |
409.15 |
0.002444091 |
22.82 |
2.282E-08 |
0.031680006 |
-1.499214739 |
137 |
410.15 |
0.002438132 |
24.61 |
2.461E-08 |
0.034164985 |
-1.466418765 |
138 |
411.15 |
0.002432202 |
26.94 |
2.694E-08 |
0.037399622 |
-1.427132787 |
139 |
412.15 |
0.002426301 |
30.92 |
3.092E-08 |
0.042924882 |
-1.367290893 |
140 |
413.15 |
0.002420428 |
33.00 |
3.300E-08 |
0.045812455 |
-1.339016439 |
141 |
414.15 |
0.002414584 |
35.01 |
3.501E-08 |
0.048602850 |
-1.31338268 |
142 |
415.15 |
0.002408768 |
39.44 |
3.944E-08 |
0.054752824 |
-1.261593472 |
143 |
416.15 |
0.002402980 |
42.00 |
4.200E-08 |
0.058306760 |
-1.234281088 |
144 |
417.15 |
0.002397219 |
48.57 |
4.857E-08 |
0.067427604 |
-1.171162275 |
145 |
418.15 |
0.002391486 |
55.95 |
5.595E-08 |
0.077672934 |
-1.109730288 |
146 |
419.15 |
0.002385781 |
65.67 |
6.567E-08 |
0.091166785 |
-1.040163362 |
147 |
420.15 |
0.002380102 |
74.70 |
7.470E-08 |
0.103702738 |
-0.984209777 |
148 |
421.15 |
0.002374451 |
79.78 |
7.978E-08 |
0.110755080 |
-0.955636347 |
149 |
422.15 |
0.002369926 |
91.18 |
9.118E-08 |
0.126581200 |
-0.897630791 |
150 |
423.15 |
0.002363228 |
99.48 |
9.827E-08 |
0.138103727 |
-0.859794602 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 3 give the following statistical data using an unweighted least squares treatment.
Slope -7182.056
Standard deviation in slope 202.532
Intercept 16.074
Standard deviation in intercept 0.490
The results obtained indicate the following vapour pressure relationship.
Log10(Vp (Pa)) = 7182.056/temp(K) + 16.074
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.015.
Run 4
Temperature (°C) |
Temperature (K) |
Reciprocal temperature (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10Vp |
128 |
401.15 |
0.002492833 |
12.26 |
1.226E-08 |
0.017020021 |
-1.769039909 |
129 |
402.15 |
0.002486634 |
13.13 |
1.312E-08 |
0.018213921 |
-1.739596544 |
130 |
403.15 |
0.002480466 |
14.38 |
1.438E-08 |
0.019963124 |
-1.699771493 |
131 |
404.15 |
0.002474329 |
15.72 |
1.572E-08 |
0.021823387 |
-1.661077837 |
132 |
405.15 |
0.002468222 |
17.24 |
1.724E-08 |
0.023933537 |
-1.620993117 |
133 |
406.15 |
0.002462145 |
17.76 |
1.776E-08 |
0.024655430 |
-1.608087417 |
134 |
407.15 |
0.002456097 |
20.49 |
2.049E-08 |
0.028445370 |
-.1.545988420 |
135 |
408.15 |
0.002450080 |
21.03 |
2.103E-08 |
0.029195028 |
-1.534691106 |
136 |
409.15 |
0.002444091 |
23.13 |
2.312E-08 |
0.032096483 |
-1.493542549 |
137 |
410.15 |
0.002438132 |
24.83 |
2.483E-08 |
0.034470401 |
-1.462553659 |
138 |
411.15 |
0.002432202 |
25.72 |
2.572E-08 |
0.035705949 |
-1.447259414 |
139 |
412.15 |
0.002426301 |
28.59 |
2.859E-08 |
0.029690245 |
-1.401316223 |
140 |
413.15 |
0.002420428 |
28.95 |
2.894E-08 |
0.040190017 |
-1.395881811 |
141 |
414.15 |
0.002414584 |
32.32 |
3.232E-08 |
0.044868440 |
-1.348059027 |
142 |
415.15 |
0.002408768 |
33.50 |
3.350E-08 |
0.046506583 |
-1.332485572 |
143 |
416.15 |
0.002402980 |
38.25 |
3.825E-08 |
0.053100800 |
-1.274898939 |
144 |
417.15 |
0.002397219 |
40.75 |
4.075E-08 |
0.056571440 |
-1.247402766 |
145 |
418.15 |
0.002391486 |
43.50 |
4.350E-08 |
0.060389145 |
-1.219041122 |
146 |
419.15 |
0.002386781 |
45.59 |
4.559E-08 |
0.063290600 |
-1.198660787 |
147 |
420.15 |
0.002380102 |
49.82 |
4.983E-08 |
0.069176806 |
-1.160039492 |
148 |
421.15 |
0.002374451 |
53.37 |
5.337E-08 |
0.074091233 |
-1.130233176 |
A plot of Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 4 gives the following statistical data using an unweighted least squares treatment.
Slope -5329.892
Standard deviation in slope 61.097
Intercept 11.524
Standard deviation in intercept 0.149
The results obtained indicate the following vapour pressure relationship.
Log10(Vp (Pa)) = -5329.892/temp(K) + 11.524
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -6.353.
Run 5
Temperature (°C) |
Temperature (K) |
Reciprocal temperature (K-1) |
Mass difference (μg) |
Mass difference (kg) |
Vapour pressure (Pa) |
Log10Vp |
150 |
423.15 |
0.002363228 |
86.00 |
8.600E-08 |
0.119390033 |
-0.923031927 |
149 |
422.15 |
0.002368826 |
66.96 |
6.696E-08 |
0.092957635 |
-1.031714934 |
148 |
421.15 |
0.002374451 |
66.00 |
6.600E-08 |
0.091624909 |
-1.037986443 |
147 |
420.15 |
0.002380102 |
57.28 |
5.728E-08 |
0.079519315 |
-1.099527369 |
146 |
419.15 |
0.002385781 |
51.98 |
5.198E-08 |
0.072161557 |
-1.141694104 |
145 |
418.15 |
0.002391486 |
46.36 |
4.636E-08 |
0.064359557 |
-1.191386951 |
144 |
417.15 |
0.002397219 |
41.38 |
4.138E-08 |
0.057446041 |
-1.240739892 |
143 |
416.15 |
0.002402980 |
36.94 |
3.694E-08 |
0.051282184 |
-1.290033488 |
142 |
415.15 |
0.002408768 |
34.12 |
3.412E-08 |
0.047367301 |
-1.324521356 |
141 |
414.15 |
0.002414584 |
31.92 |
3.192E-08 |
0.044313138 |
-1.353467496 |
140 |
413.15 |
0.002420428 |
27.44 |
2.744E-08 |
0.038093750 |
-1.419146272 |
A plot Log10(vapour pressure (Pa)) versus reciprocal temperature (1/T(K)) for Run 5 gives the following statistical data using an unweighted least squares treatment.
Slope -8114.666
Standard deviation in slope 291.807
Intercept 18.221
Standard deviation in intercept 0.698
The results obtained indicate the following vapour pressure relationship.
Log10(Vp (Pa)) = -8114.666/temp(K) + 18.221
The above yields a vapour pressure (Pa) at 298.15 K with a common logarithm of -8.996.
Summary of Results
Run |
Log10 [Vp(25°C)] |
1 |
-7.233 |
2 |
-6.826 |
3 |
-8.015 |
4 |
-6.353 |
5 |
-8.996 |
Mean = -7.485 Vapour Pressure = 3.3 x 10-8 Pa |
The test material did not change in appearance under the conditions used in the determination.
Description of key information
APAN has been determined to have a vapour pressure of 3.3 x 10-8Pa at 25 °C, using a vapour pressure balance.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 25 °C
Additional information
The test procedure was based on Method A4 specified in Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
APAN has been determined to have a vapour pressure of 3.3 x 10-8 Pa at 25 °C, using a vapour pressure balance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.