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Diss Factsheets
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EC number: 824-774-1 | CAS number: 148124-40-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
EDTA is not readily biodegradable according to OECD criteria. In standard OECD 301D tests, EDTA complexes with a stability constant lower than 10E13 like EDTA-Na4, EDTA-CaNa2, EDTA-MnK2 etc. less than 60% biodegradation was observed after 28 days indicating that these substances should be not classified as readily biodegradable but in the same tests > 60% biodegradation was observed after 60 days in the prolonged (enhanced) tests indicating that these compexes, having stability constants < 10E13, are not persistent.
The EDTA-Fe(OH)K2 complex has a stability constant >10E12 and is therefore expected to be persistent according to OECD criteria, when tested in standard ready biodegradability tests. At lower environmentally more representative concentrations however significant biodegradation may occur. The level of this stability constant threshold dependents on the concentration balance between the starting complex and free metal ions (alkali and alkaline earth metals) in the matrix. The lower the starting concentration of the EDTA-metal complex the higher this stability constant threshold for biodegradation. EDTA-Iron complexes have a stability constant close to 10E23 and are expected to be persistent in standard ready biodegradability tests also at much lower test concentrations. The EDTA-Iron complexes are however senstive to photodegradation and at pH>7, iron tends to precipitate as Iron hydroxides liberating EDTA for degradation. The higher the pH the higher the decomplexation rate.
Additional information
EDTA is not readily biodegradable according to OECD criteria. It was shown that with natural river water as inoculum, in standard OECD 301D tests, EDTA complexes with a stability constant lower than 10E13 like EDTA-Na4, EDTA-CaNa2, EDTA-MnK2 etc. less than 60% biodegradation was observed after 28 days indicating that these substances should be not classified as readily biodegradable but in the same tests > 60% biodegradation was observed after 60 days in the prolonged (enhanced) tests indicating that these compexes, having stability constants < 10E13, are not persistent.
This stability constant threshold of 10E13 will be dependent on the concentration balance between the starting complex and free metal ions (alkali and alkaline earth metals). The lower the starting concentration of the EDTA-metal complex the higher this stability constant threshold for biodegradation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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