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EC number: 638-734-4 | CAS number: 157248-24-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011-04-06 to 2011-05-26
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- 2008
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- 2006
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- effusion method: vapour pressure balance
- Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- 0.001 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 25 °C
- Vapour pressure:
- 0.001 Pa
- Key result
- Test no.:
- #3
- Temp.:
- 50 °C
- Vapour pressure:
- 0.14 Pa
- Conclusions:
- The vapour pressures for the solid form of the test item were determined to be 5.0*10^-4 Pa (20 °C), 1.4*10^-3 Pa (25 °C) and 1.4*10^-1 Pa (50 °C).
- Executive summary:
A study was performed according to OECD TG 104 and Commission Regulation (EC) No. 440/2008, method A.4 in order to determine the vapour pressure of the test item by using the effusion method (vapour pressure balance). The vapour pressure was measured at various temperatures between 17 and 92 °C. The vapour pressure data showed an unusual behaviour with a two-staged curve shape. Based on the DSC measurements the different curve shapes were supposed to be due to the respective state of the test item. One curve shape was observed in the temperature range 32 - 48 °C for the test item in its solid form. In the temperature range 53 - 92 °C the second curve shape for the test item in its liquid form was determined. The vapour pressures of the test item at 20, 25 and 50 °C were extrapolated by using the Antoine constants. As final results the calculated extrapolated values of the vapour pressure in the lower temperature range (32 – 48 °C, solid form of the test item) were: 5.0*10^-4 Pa (20 °C), 1.4*10^-3 Pa (25 °C) and 1.4*10^-1 Pa (50 °C).
Reference
Thermal Stability
The DSC-measurement in a closed glass crucible showed an endothermic effect in the temperature range of 45 – 65 °C and no exothermal effect until the maximum test temperature of 350 °C.
Vapour Pressure Balance (Effusion Method)
The vapour pressure was measured in the temperature range of 17 °C to 92 °C. Above 27 °C a vapour pressure could be measured. The measured vapour pressures at the corresponding temperatures are listed in the following table:
Temperature / °C | Vapour pressure / hPa |
*1) 31.6 | 4.2 x 10^-5 |
*1) 35.9 | 1.2 x 10^-4 |
*1) 39.8 | 2.9 x 10^-4 |
*1) 42.8 | 4.3 x 10^-4 |
*1) 47.7 | 7.8 x 10^-4 |
*2) 52.6 | 8.7 x 10^-4 |
*2) 58.7 | 1.8 x 10^-3 |
*2) 66.3 | 3.9 x 10^-3 |
*2) 73.9 | 8.7 x 10^-3 |
*2) 79.8 | 1.6 x 10^-2 |
*2) 85.1 | 2.7 x 10^-2 |
*2) 92.1 | 5.4 x 10^-2 |
*1) due to the results of the DSC measurement, it is supposed that the test item exists in its solid form
*2) due to the results of the DSC measurement, it Is supposed that the test item exists in its liquid form
The vapour pressure data showed an unusual behaviour with a two-staged curve shape. For the vapour pressure the regression to determine the coefficient of the Antoine equation A, B, C was done for the two stages of the curve separately. First for the curve shape in the temperature range 32 - 48 °C where due to the results of the DSC measurement, it is supposed that the test item exists in its solid form*1), and second for the curve shape in the temperature range 53 - 92 °C where it is supposed that the test item exists in its liquid form*2).
The values for 20, 25 and 50 °C are calculated, using the Antoine constants A, B and C.
In the temperature range 32 - 48 °C following constants were determined: A=21.09875, B=-7740.32, C=273.15. Vapour pressures of 4.95*10^-6 hPa at 20 °C, 1.37*10^-5 hPa at 25 °C and 1.4*10^-3 hPa at 50 °C were determined.
In the temperature range 53 - 92 °C following constants were determined: A=13.36243, B=-5350.62, C=273.15. Vapour pressures of 1.29*10^-5 hPa at 20 °C, 2.61*10^-5 hPa at 25 °C and 6.38*10^-4 hPa at 50 °C were determined.
Description of key information
The vapour pressures for the solid form of the test item were determined to be 5.0*10^-4 Pa (20 °C), 1.4*10^-3 Pa (25 °C) and 1.4*10^-1 Pa (50 °C).
Key value for chemical safety assessment
- Vapour pressure:
- 0.001 Pa
- at the temperature of:
- 20 °C
Additional information
A study was performed according to OECD TG 104 and Commission Regulation (EC) No. 440/2008, method A.4 in order to determine the vapour pressure of the test item by using the effusion method (vapour pressure balance). The vapour pressure was measured at various temperatures between 17 and 92 °C. The vapour pressure data showed an unusual behaviour with a two-staged curve shape. Based on the DSC measurements the different curve shapes were supposed to be due to the respective state of the test item. One curve shape was observed in the temperature range 32 - 48 °C for the test item in its solid form. In the temperature range 53 - 92 °C the second curve shape for the test item in its liquid form was determined. The vapour pressures of the test item at 20, 25 and 50 °C were extrapolated by using the Antoine constants. As final results the calculated extrapolated values of the vapour pressure in the lower temperature range (32 – 48 °C, solid form of the test item) were: 5.0*10^-4 Pa (20 °C), 1.4*10^-3 Pa (25 °C) and 1.4*10^-1 Pa (50 °C).
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