Registration Dossier
Registration Dossier
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EC number: 247-361-2 | CAS number: 25952-53-8
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 13 November 2017 to 14 November 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7950 (Vapor Pressure)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- effusion method: isothermal thermogravimetry
- Specific details on test material used for the study:
- - Source and lot/batch No.of test material: Sponsor and AAN0680
- Expiration date of the lot/batch: 30 August 2018
- Purity test date: 09 September 2016 - Key result
- Test no.:
- #1
- Temp.:
- 20 °C
- Vapour pressure:
- < 0.002 Pa
- Key result
- Test no.:
- #2
- Temp.:
- 20 °C
- Vapour pressure:
- < 0 mm Hg
- Key result
- Test no.:
- #3
- Temp.:
- 25 °C
- Vapour pressure:
- < 0.004 Pa
- Key result
- Test no.:
- #4
- Temp.:
- 25 °C
- Vapour pressure:
- 0 mm Hg
- Conclusions:
- The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride.
The vapour pressure of the test item was: < 1.5E-3 Pa (< 1.1E-5 mmHg) at 20°C (293K) and < 4E-3 Pa (< 3.0E-5 mmHg) at 25°C (298K).
Reference
See attached for detailed results of isothermal TGA analysis
Description of key information
The isothermal TGA effusion method was applied for the determination of the vapour pressure of 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride.
The vapour pressure of the test item was: < 1.5E-3 Pa (< 1.1E-5 mmHg) at 20°C (293K) and < 4E-3 Pa (< 3.0E-5 mmHg) at 25°C (298K).
Key value for chemical safety assessment
- Vapour pressure:
- 0.002 Pa
- at the temperature of:
- 20 °C
Additional information
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