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EC number: 635-156-4 | CAS number: 109293-98-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Key study with freshwater diatom, navicula pelliculosa:
The 5-day EC50 was calculated to be 0.10 mg A.E./L (95% confidence limits of 0.033 and 0.36 mg A.E. (acid equivalent)/L). The 5-day No-Observed-Effect Concentration (NOEC) was determined to be 0.0030 mg A.E. (acid equivalent)/L.
Key study with marine water diatom, Skeletonems costatum:
The effects of the test substance observed on the growth of Skeletonema costatum were clearly concentration related and yielded a 5-day EC50 value, based on cell density, of 0.14 mg A.E.(acid equivalent)/L. The 5-day No-Observed-Effect Concentration (NOEC) was determined to be 0.0064 mg A.E. (acid equivalent)/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.1 mg/L
- EC50 for marine water algae:
- 0.14 mg/L
- EC10 or NOEC for freshwater algae:
- 0.003 mg/L
- EC10 or NOEC for marine water algae:
- 0.006 mg/L
Additional information
Key study (freshwater diatom)
A 5-day toxicity test with the freshwater diatom, navicula pelliculosa was performed in accordance with FIFRA Guidelines 122-2 and 123-2. The mean measured concentration were: 0.0030, 0.0052, 0.011, 0.024, 0.042, 0.084 and 0.17 mg A.E. (acid equivalent)/L.
Based on the analytical results generated during this study, the concentrations of the test substance (difluenzopyr sodium salt) were relatively stable during the 5-day exposure period. The mean measured test concentrations ranged from 83 to 96% of nominal concentrations. Based on mean measured concentrations, the 5-day EC50 was calculated to be 0.10 mg A.E.(acid equivalent)/L (95% confidence limits of 0.033 and 0.36 mg A.E.(acid equivalent)/L). The 5 -day No-Observed-Effect Concentration (NOEC) was determined to be 0.0030 mg A.E.(acid equivalent)/L.
In addition to the worst case key study, several supporting studies with diverse algae species (Anabaena flos-aquae and Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) were performed according to FIFRA guidelines 122 -2 and 123 -2 (guidelines equivalents to US. EPA, 1982). The measured reference figures support the findings of the key study. NOEC values were in the range of 0.0064 mg/L to 0.0078 mg/L. EC50 values were between 0.11 mg/L and 0.14 mg/L.
Key study (marine water diatom):
A 5-day toxicity test with the marine diatom, Skeletonems costatum, was performed in acordance with FIFRA guidelines 122-2 and 123-2. Based on the analytical results generated during this study, the concentrations of the test subbstance were relatively stable during the 5-day exposure period. The mean measured test concentrations of the test substance (difluenzopyr sodium salt) ranged from 87 to 100% of nominal concentration. The mean measured concentrations were: 0.0064, 0.013, 0.024, 0.043, 0.092 and 0.18 mg A.E. (acid equivalent)/L.The effects of the test substance observed on the growth of Skeletonema costatum were clearly concentration related and yielded a 5-day EC50 value, based on cell density, of 0.14 mg A.E. (acid equivalent)/L (corresponding 95% confidence limits of 0.075 to 0.27 mg A.E. (acid equivalent)/L). The 5-day No-Observed-Effect Concentration (NOEC) was determined to be 0.0064 mg A.E.(acid equivalent)/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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