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EC number: 231-633-2 | CAS number: 7664-38-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Literature data are available to assess the effects of phosphoric acid on fish. Studies are not performed to an OECD guideline but are considered ot be reliable for assessment (Klimisch 2) as part of a weight of evidence in accordance with Annex XI of Regulation (EC) No. 1907/2006 (REACH). These studies indicate that mortality as a result of phosphoric acid exposure is linked to the pH and not as a result of systemic toxicity.
Key value for chemical safety assessment
Additional information
A Median lethal pH (96h) of 3-3.25 for Lepomis macrochirus (no guideline followed) has been derived.
All available studies show that mortality is caused by low pH values. When adjusted to environmentally relevant pH values, phosphoric acid does not cause acute adverse effects.
The study from Ellgaard and Gilmore 1982, focuses on the pH effects caused by phosphoric acid. Different pH levels have been tested in bluegill sunfish.
The pH induced by phosphoric acid which caused 50% mortality was between 3.0 and 3.25, while no mortality was observed at pH 3.5 or above after 96h exposure. At neutral pH 7.5 no fish died.
Similar results were obtained in the Alkahem study: a median lethal pH of 3.58 in Aphanius dispar. The Korean study showed a 96h-LC50 of phosphoric acid in Oryzias latipes of 75.1 mg/L, but the pH was not adjusted to relevant environmental values. No mortality was observed at 100 mg/L when the pH was adjusted.
The studies show that a pH caused by adding phosphoric acid roughly between pH 3 (or lower) and 4 is critical for fish. The Gueylard and Duval study showed that survival times increased with increasing pH, and that this increase was more rapid at pH values above 3.5. It can thus be concluded that it is the low pH which is causing the toxic effects. Wallen et al. cited by Von Burg as well described a study in which fish (Gambusia affinis) were exposed to both phosphoric acid and turbidity (600 ppm of clay particles), and in which phosphoric acid precipitated turbidity to levels below 25 ppm. The median tolerance limit after 24, 48 and 96h exposure was 138 ppm (i.e. about 138 mg/L). Townsend and Cheyne (1944) showed that exposure of Oncorhynchus kisutch fingerlings to 20 ppm of phosphoric acid (i.e. pH 6.75) induced no mortality at relatively normal dissolved oxygen concentrations (4.95 -8.15 ppm). However, when the dissolved oxygen concentration was lowered to 1.50 ppm, phosphoric acid at 12.0 and 20.0 ppm induced 100% mortality, which is obviously caused by the combination of the low dissolved oxygen concentration and the presence of increased hydrogen ion concentrations.
As regulatory ecotoxicity tests need to be conducted at pH 6-9, it can be expected that phosphoric acid will not cause adverse effects to fish when in this pH range.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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