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EC number: 407-420-7 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The comparison of the results for the parameter of concern for PART I and II of the study showed no dose response relationship. Therefore it is demonstrated that the observed difference exceeding the 10% level is due to test design depending data variability. Based on this arguments the inhibition of growth observed in this study is due to algistatic effects caused by light absorption only.
Key value for chemical safety assessment
Additional information
A study was performed to assess the adverse effects of test substance on the growth and growth rate of the planktonic freshwater algal species Desmodesmus subspicatus over several generations. The study was conducted in accordance with EU Method C.3., OECD Guideline 201 and an instruction for the performance of a modified algal growth inhibition test published by Memmert & Knoell.
Exponentially growing algal cells were exposed for a period of 72 hours to a range of concentrations, nominally 0.4, 1.0, 2.1, 4.6, 10.3, 22.7 and 50 mg/L of test substance dissolved in water (PART I). A second series (PART II) of test vessels treated in the same way as the controls, but placed below glass vessels containing the same range of concentrations of the test substance as described above, but without algae, was set up to distinguish between algistatic (indirect effect caused by light absorption) and algicide (toxic) effects.The cell densities were measured at 24 h intervals. Inhibition of the algal population was measured as reduction in growth (index b) and growth rate (index r), relative to control.
All results are expressed in terms of nominal concentrations. Measured concentrations ranged from 83 - 101 % of nominal values at 0 h, and from 76 - 88 % of nominal values at 72 h, respectively.
Results [mg/L]: |
PART I |
PART II |
EbC 50 (0-72h) |
3.6 |
5.6 |
ErC 50 (0-72h) |
14 |
14 |
NOEC [b] |
0.4 |
2.1 |
LOEC [b] |
1.0 |
4.6 |
NOEC [r] |
2.1 |
2.1 |
LOEC [r] |
4.6 |
4.6 |
A comparison of the results for the parameter "percentage inhibition of the growth rate" gained in PART I and II of the study results in no differences exceeding 10% with the exception of the results for the concentration 1 mg/L. For this concentration a difference of 13.5% between the "percentage inhibition of the growth rate" for PART I and II of the study was estimated. This value is caused by an increased algae growth in the test substance concentration 1 mg/L (PART II) compared to the control.
The comparison of the results for the parameter of concern for PART I and II of the study showed no dose response relationship. Therefore it is demonstrated that the observed difference exceeding the 10% level is due to test design depending data variability. Based on this arguments the inhibition of growth observed in this study is due to algistatic effects caused by light absorption only.
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