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EC number: 941-220-5 | CAS number: 1126076-86-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2015
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Nominal concentrations (WAF method) - because sensitive analytical method could not be developed.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 015
- Report date:
- 2015
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.3 (Algal Inhibition test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- Reaction mass of 2,9-dimethoxy-5,12-dihydroquino[2,3-b]acridine-7,14-dione and 2,9-dichloro-5,12-dihydroquino[2,3-b]acridine-7,14-dione
- EC Number:
- 941-220-5
- Cas Number:
- 1126076-86-5
- Molecular formula:
- PV54: C22H16N2O4 PR202: C20H10Cl2N2O2
- IUPAC Name:
- Reaction mass of 2,9-dimethoxy-5,12-dihydroquino[2,3-b]acridine-7,14-dione and 2,9-dichloro-5,12-dihydroquino[2,3-b]acridine-7,14-dione
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- EL50
- Effect conc.:
- > 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Remarks on result:
- other: WAF prepared at the given loading rate
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- The EL50 for inhibition of both growth rate (72h-ERL50) and yield (72h-EYL50) was above 100 mg/l.
- Executive summary:
Pseudokirchneriella subcapitata, Fresh Water Algal Growth Inhibition Test with C. I. Pigment Violet 55.
The study procedures described in this report were based on the OECD guideline No. 201, 2006; Annex 5 corrected 28 July 2011. In addition, the procedures were designed to meet the test methods of theCommissionRegulation (EC) No 440/2008, Part C.3, 2008; Amended by EC No. 761/2009and the OECD series on testing and assessment number 23, 2000.
The batch of C. I. Pigment Violet 55 tested was a violet powder and not completely soluble in test medium at the initial loading rates prepared.No correction was made for the purity/composition of the test substance.
Preparation of test solutions started with loading rates of 1.0, 10 and 100 mg/l applying two days of magnetic stirring to reach the maximum solubility of the test substance in the test medium. The resulting aqueous mixtures were filtered through a 0.45 µm membrane filter and the Water Accommodated Fractions (WAFs) were used as test concentrations.The WAF prepared at a loading rate of 1.0 mg/l was observed to be clear and colourless. The WAFs prepared at loading rates of 10 and 100 mg/l were observed to be clear and slightly purple.
A combined limit/range-finding test was performed.Six replicates of exponentially growing algal cultures were exposed to a control and to a WAF prepared at a loading rate of 100 mg/l. In addition, three replicates per group were exposed toWAFs prepared at loading rates of 1.0 and 10 mg/l. The initial cell density was 104cells/ml and the total exposure period was 72 hours. The study did not include sampling for determination of actual exposure concentrations.
From 48 hours of exposure onwards test substance particles were observed in the WAFs prepared at 10 and 100 mg/l. In addition, after 72 hours of exposure a floating layer was observed at both WAFs. Test concentration in these two WAFs were therefore above the solubility limit in test medium.
The study met the acceptability criteria prescribed by the protocol and was considered valid.
Due to the low solubility of C. I. Pigment Violet 55 in test medium, concentration levels that might be toxic for algae could not be reached.
The EL50for inhibition of both growth rate (72h-ERL50) and yield (72h-EYL50) was above 100 mg/l.
The 72h-NOELR for growth rate inhibition was above 100 mg/l. The 72h-NOELR for yield inhibition was above 10 mg/l.
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