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EC number: 226-134-1 | CAS number: 5292-45-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: well performed OECD study with GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
- Report date:
- 2000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Dimethyl 2-nitroterephthalate
- EC Number:
- 226-134-1
- EC Name:
- Dimethyl 2-nitroterephthalate
- Cas Number:
- 5292-45-5
- Molecular formula:
- C10H9NO6
- IUPAC Name:
- dimethyl 2-nitroterephthalate
- Details on test material:
- purity:98.1 %
expiry: 2001-09-30
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- The activated sludge is maintained in an aerobic condition by aeration for four hours and then homogenized with a mixer. The sludge is filtered and the filtrate (3o mL) is subsequently used to initiate inocculation.
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 25 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- test temperature: 23 - 24 °C
- pH: about 7.5
- pH adjusted: no
TEST SYSTEM
- Culturing apparatus: 5000 ml vessel (brown glass); test volume 3000 ml
- Measuring equipment: pH-meter; Corning pH 240
- Test performed in open system: no
- Details of trap for CO2 and volatile organics if used: Ba(OH)2 solution
CONTROL AND BLANK SYSTEM
- Inoculum blank: Nutrient solution and inoculum
- Functional control: Sodium acetate
- Toxicity control: test item plus reference substance
Reference substance
- Reference substance:
- other: sodium acetate
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 6 - 7
- Sampling time:
- 6 d
- Remarks on result:
- other: values of replicate 1 and 2
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 11 - 22
- Sampling time:
- 14 d
- Remarks on result:
- other: values of replicate 1 and 2
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 11 - 30
- Sampling time:
- 21 d
- Remarks on result:
- other: values of replicate 1 and 2
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 11 - 37
- Sampling time:
- 28 d
- Remarks on result:
- other: values of replicate 1 and 2
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradable
- Conclusions:
- base on the results of the OECD 301 B test, Nitro-DMT must be considered as not readily biodegradable
- Executive summary:
The ready biodegradability was determined with a non adapted activated sludge with Nitro-DMT over a period of 28 days in the Modified Sturm Test (OECD 301B). The test item was tested in a concentration of 25 mg/L in duplicate and the biodegradation was followed by the titrimetric analysis of the quantity of CO2, which was produced by the respiration of the bacteria. The CO2 production was calculated as the percentage of total CO2, that the test item could have theoretically produced, based on the carbon composition.
After 28 days the biodegradation came to a level of 11 - 37 %.
Sodium acetate was used as functional control. The degradation wti this reached > 60 % after 6 days.
In the toxicity control (test item plus reference substance) the biodegradation came to a maximum of 40% after days. The biodegradation of the reference substance seemd not to be inhibited by the test item.
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