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EC number: 601-779-5 | CAS number: 121451-02-3
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 22 August 2000
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from the standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and conducted under GLP conditions.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- capillary method
- Key result
- Melting / freezing pt.:
- 156.2 °C
- Atm. press.:
- ca. 1 013 hPa
- Decomposition:
- no
- Sublimation:
- no
- Conclusions:
- Under the conditions of the test, the test melting point of the test material was determined to be 156.2 °C.
- Executive summary:
The melting point of the test material was determined in triplicate using Thomas Hoover capillary melting point apparatus in a GLP study conducted in accordance with test guideline EPA OPPTS 830.7200. The apparatus was allowed to cool between measurements. The test material was placed in a small capillary, packed and placed in the melting point apparatus. The temperature of the oil bath was slowly raised at approximately 0.4 to 0.8 °C/min. The temperature was recorded when the material softened and when it complexly melted. The apparatus was calibrated using benzoic acid. Under the conditions of the test, the test melting point of the test material was determined to be 156.2 °C.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 11 October 2000 - 8 December 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from the standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and conducted under GLP conditions.
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7200 (Melting Point / Melting Range)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- hot stages
- Remarks:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- > 155 - < 157 °C
- Decomposition:
- yes
- Decomp. temp.:
- ca. 250 °C
- Sublimation:
- no
- Conclusions:
- Under the conditions of the test, the meltnig point of the test material was determined to be in the range of 155 to 157 °C.
- Executive summary:
The melting point of the test material was determined in a study performed under GLP conditions and in line with the standardised guideline EPA OPPTS 830.7200 using the differential scanning calorimetry (DSC method). Under the conditions of the test, the melting point range of the test material was determined to be 155 - 157 °C.
Referenceopen allclose all
Table 1: Results
Material |
Replicate |
Temperature (°C) |
Average melting point (°C) |
|
Soften |
Melting point |
|||
Reference Substance |
1 |
120.2 |
121.6 |
121.7* |
2 |
120.0 |
121.8 |
||
3 |
120.2 |
121.8 |
||
Test Material |
1 |
155.0 |
156.2 |
156.2 |
2 |
155.0 |
156.2 |
||
3 |
155.0 |
156.2 |
* The average melting point of benzoic acid is within 1 °C of the expected melting point of 122.2 °C.
The DSC scan of the test material reported a melting point range of 155 - 157 °C. A representative thermogram is shown in Figure 1.
Description of key information
Melting point 156.2 °C, capillary method, EPA OPPTS 830.7200, Busse 2000.
Melting point 155 - 157 °C, DSC method, EPA OPPTS 830.7200, Busse 2001.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 156 °C
Additional information
The melting point of the test material has been addressed using a weight of evidence, consisting of two GLP guideline studies. Both studies have been assigned a reliability score of 1, reliable without restrictions, in line with the principles of Klimisch et al. (1997). The studies are in agreement that the melting point of the test material lies in the range of 155 – 157 °C. The melting point has been reported as 156 °C.
In the first study (Busse, 2000) the melting point of the test material was determined in triplicate using Thomas Hoover capillary melting point apparatus in a GLP study conducted in accordance with test guideline EPA OPPTS 830.7200.
The test material was placed in a small capillary, packed and placed in the melting point apparatus. The temperature of the oil bath was slowly raised at approximately 0.4 to 0.8 °C/min. The temperature was recorded when the material softened and when it complexly melted. The apparatus was calibrated using benzoic acid. Under the conditions of the test, the test melting point of the test material was determined to be 156.2 °C.
In the second study (Busse, 2001) the melting point of the test material was determined in a study performed under GLP conditions and in line with the standardised guideline EPA OPPTS 830.7200 using the differential scanning calorimetry (DSC method).
Under the conditions of the test, the melting point range of the test material was determined to be 155 - 157 °C.
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