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EC number: 610-949-8 | CAS number: 53045-70-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
The incubated hen egg test revealed a high irritation index. Therefore, the substance was classified as skin corrosion cat. 1A and serious eye damage cat. 1.
Key value for chemical safety assessment
Skin irritation / corrosion
Link to relevant study records
- Endpoint:
- skin irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- Only a brief summary of the study is available
- Qualifier:
- according to guideline
- Guideline:
- other: Hen's egg test
- GLP compliance:
- not specified
- Irritation / corrosion parameter:
- other: hen egg irritation score
- Value:
- ca. 19.09
- Remarks on result:
- other: The substance was evaluated in a hen egg irritation assay.
Reference
Before testing the test item in rabbits, an alternative method, i.e. the Hen's egg test (HET), was used for an evaluation of possible skin irritating properties of the test item. The irritation scores in this test are:
0 – 0.9: not irritating
1 – 4.9: slightly irritating
5 – 8.9: moderately irritating
9 – 21: severely irritating.
The test revealed an irritation score of 19.09, i.e. a corrosive or severe irritating potential can be expected. Therefore, no in vivo study with rabbits was performed.
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (corrosive)
Eye irritation
Link to relevant study records
- Endpoint:
- eye irritation: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with national standard methods with acceptable restrictions
- Remarks:
- Only a brief summary of the study is available
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The hen egg irritation score was determined.
- GLP compliance:
- not specified
- Irritation parameter:
- other: Hen egg irritation score
- Value:
- 19.09
- Remarks on result:
- other: The hen egg irritation score was determined.
Reference
Before testing the test item in rabbits, an alternative method, i.e. the Hen's egg test (HET), was used for an evaluation of possible eye irritating properties of the test item. The irritation scores in this test are
0 – 0.9: not irritating
1 – 4.9: slightly irritating
5 – 8.9: moderately irritating
9 – 21: severely irritating.
The test revealed an irritation score of 19.09, i.e. a corrosive or severe irritating potential can be expected. Therefore, no in vivo study with rabbits was performed.
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irreversible damage)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
The test material showed high potential for skin corrosion and eye damage in the hen egg pretest. Therefore, the test material should be classified as skin corrosive cat. 1A and eye damaging cat. 1.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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