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Diss Factsheets
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EC number: 200-752-1 | CAS number: 71-41-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Aquatic toxicity
Short-term toxicity to fish
A publication is available describing the toxicity of the test substance on Danio rerio after 96 hours of exposure. The study was performed according to OECD Draft 1980 and ISO TC 147/SCS/WG3 final proposal and revealed a LC50 of 530 mg/L. In addition study data of other category members are available all revealing LC50 values well above 100 mg/L.
Long-term toxicity to fish
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms. According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the criteria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB. The hazard assessment of pentan-1-ol reveals neither a need to classify the substance as dangerous for the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore, and for reasons of animal welfare, a long-term toxicity study in fish is not provided.
Short-term toxicity to aquatic invertebrates
The short term toxicity to aquatic invertebrates was evaluated using a weight of evidence approach. The 48 h-EC50 value of 255 mg /L determined in a study conducted with the read-across substance 3-methylbutan-1-ol according to DIN 38412 L11 was chosen as key parameter. In addition study results are available for all the other category members, all revealing EC50 values well above 100 mg/L.
Long-term toxicity to aquatic invertebrates
In Annex IX of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity testing shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on aquatic organisms.
According to Annex I of this regulation, the chemical safety assessment triggers further action when the substance or the preparation meets the crit eria for classification as dangerous according to Directive 67/548/EEC or Directive 1999/45/EC or is assessed to be a PBT or vPvB.
The hazard assessment of pentan-1-ol reveals neither a need to classify the substance as dangerous for the environment, nor is it a PBT or vPvB substance, nor are there any further indications that the substance may be hazardous to the environment. Therefore a long-term toxicity study in aquatic invertebrates is not provided.
Toxicity to algae and cyanobacteria
The influence of the test substance on the growth of the freshwater algae Scenedesmus quadricauda was assessed in a static dose response test. The 8 days EC50 was determined to be 260 mg test item/L. In addition study results are available for the other category members, revealing EC50 and EC10 values well above 100 mg/L.
Toxicity to aquatic plants other than algae
Data on toxictiy to aquatic plant other than algae are not required for REACh registration.
Toxicity to microorganisms
The toxic effects of the surrogate test substances pentanol, branched and linear (CAS 94624-12-1) and 2-methylbutan-1-ol were determined based on the oxygen consumption rate of aerobic micro-organisms (activated sludge) after short-term exposure of 180 min according to the OECD test guideline 209. Read across was applied using these results and the EC50 of the test substance was determined to be greater than 1000 mg/L and the EC10 was determined to be 370 mg/L.
Toxicity to other aquatic organisms
No requirement under REACh
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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