Registration Dossier
Registration Dossier
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EC number: 253-781-7 | CAS number: 38103-06-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, non-adapted
- Details on inoculum:
- Secondary effluent from Lulu Island Domestic Wastewater Treatment plant, Richmond, BC
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 10 mg/L
- Based on:
- test mat.
- Reference substance:
- benzoic acid, sodium salt
- Preliminary study:
- Test material did not pass out of the acclimation phase during the evaluation.
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0.6
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0.8
- Sampling time:
- 14 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- -0.6
- Sampling time:
- 21 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- -0.2
- Sampling time:
- 24 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- -1.6
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not readily biodegradable
- Conclusions:
- Under the conditions of this study, no significant biodegradation was observed.
- Executive summary:
The potential for the test material to undergo biodegradation was investigated in a closed bottle test conducted in accordance with OECD 301 under GLP conditions.
Non-adapted activated sludge was exposed to the test material under aerobic conditions for 28 days.
Under the conditions of this study, no significant biodegradation was observed.
Reference
Description of key information
Under the conditions of the study the test material was determined to be not readily biodegradable.
In accordance with section 9.2 of Column 2 of REACH Annex IX, further degradation studies are only needed if indicated as necessary based on the result of Chemical Safety Assessment. For this registration, the Chemical Safety Assessment does not indicate a need for such further studies. Therefore, it is considered justified to omit testing for the identification of degradation products.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
The potential for the test material to undergo biodegradation was investigated in a closed bottle test conducted in accordance with OECD 301 under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
Non-adapted activated sludge was exposed to the test material under aerobic conditions for 28 days.
Under the conditions of this study, no significant biodegradation was observed.
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