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Diss Factsheets
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EC number: 234-521-1 | CAS number: 12007-89-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- other: Case study
- Adequacy of study:
- supporting study
- Study period:
- No data
- Reliability:
- other: Case study
- Rationale for reliability incl. deficiencies:
- other: Not applicable as this is a case study.
Data source
Reference
- Reference Type:
- publication
- Title:
- Accidental boric acid poisoning following the ingestion of household pesticide.
- Author:
- Hamilton RA & Wolf BC
- Year:
- 2 007
- Bibliographic source:
- J. Forensic Sci. 52 (3) 706 – 8
Materials and methods
- Study type:
- poisoning incident
- Endpoint addressed:
- acute toxicity: oral
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- The reference describes a poisoning incident in humans.
- GLP compliance:
- no
Test material
- Reference substance name:
- Boric acid
- EC Number:
- 233-139-2
- EC Name:
- Boric acid
- Cas Number:
- 10043-35-3
- Molecular formula:
- H3BO3
- IUPAC Name:
- Boric acid
- Details on test material:
- - Name of test material: Boric acid-containing roach powder.
Constituent 1
Method
- Subjects:
- Number of subjects exposed: One
- Sex: Female
- Age: 18-months old
- Known diseases: The child had no documented past medical history. - Route of exposure:
- oral
- Reason of exposure:
- accidental
- Exposure assessment:
- measured
Results and discussion
- Clinical signs:
- The child was pronounced dead at the emergency room. No clinical signs were therefore described.
- Results of examinations:
- A post-mortem examination was performed 28 h after the child’s death. The stomach contained 80 cc of thick green-brown liquid and the small and large intestines focally contained a light brown, liquid material. Routine toxicological studies were negative. A heart-blood borate concentration of 8316 mcg/dL (reference range toxic > 2000 mcg/dL) and a gastric content borate concentration of 6048 mg/L.
Applicant's summary and conclusion
- Conclusions:
- The case of an 18-month-old child who died following the accidental ingestion of boric acid-containing commercially available roach pesticide product was described. A post-mortem examination was performed 28 h after the child’s death. The stomach contained 80 cc of thick green-brown liquid and the small and large intestines focally contained a light brown, liquid material. Routine toxicological studies were negative. A heart blood borate concentration of 8316 mcg/dL (reference range toxic > 2000 mcg/dL) and a gastric content borate concentration of 6048 mg/L. The cause of death was attributed to accidental acute borax toxicity.
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