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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Description of key information

The BCF of oleic-acid based IQAC, DMS quaternised is 10.7.

Key value for chemical safety assessment

BCF (aquatic species):
10.7 dimensionless

Additional information

The calculation of BCFs via BCFBAF v3.01 for oleic-acid based IQAC, DMS quaternised yielded values in the range between 1 (Arnot-Gobas calculation method (upper trophic)) and 71 L/kg wet-wt (regression-based calculation method). Based on the calculated BCFs a low potential for bioaccumulation is to be expected for oleic-acid based IQAC, DMS quaternised. This is supported by the fast hydrolysis and inherent biodegradability of the substance and the results of three toxicokinetical studies with mammals (rats) indicating poor absorption (dermal and intestinally) and fast elimination. For the closely related structural homologue (partially unsaturated IQAC, DMS quaternised, CAS-No. 68122-86-1) a flow through study with bluegill sunfish indicated a low bioaccumulation potential (BCF = 10.7) of IQAC. It is expected, that both substances have the same BCF, as there is no significant difference in relevant phys.-chem. properties (for example equilibrium partitioning), as well as no relevant difference is expected for metabolism.

The publication of the Australian state authority for the registration of chemical substances NICNAS was used for the determination of the BCF, used for the chemical safety assessment (CSA). This was done because the published BCF is based on measured data (fish test) and therefore seems to be more reliable.