Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 813-130-5 | CAS number: 4039-86-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In the static immobilization test, young Daphnia magna STRAUSS (< 24 h old) were exposed to the test item for 48 hours according to OECD 202 (2004). The EC50 value was determined to be nominal 9.29 mg test item/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 9.29 mg/L
Additional information
The acute toxicity of the test substance to Daphnia magna (STRAUS) was determined in a study (BASF SE, 2016) according to OECD 202 (2004). The effects of the test substance with a nominal loading of 0 (control), 0.46, 1.0, 2.2, 4.6 and 10 mg/L were determined under GLP conditions. The corresponding mean measured concentrations of the test substance were determined to be 0.441, 0.958; 2.134, 4.469, 9.825 mg/L. The study encompassed 4 replicates per concentration and 1 replicate per control. The number of the organisms per vessel was 5. The mobility of the Daphnia was determined in a static test by visual observation after 24 and 48 hours. The stock solution was prepared by directly adding of the test substance to the test medium and stirring for about one day. No undissolved test substance was observed. The lower test concentrations were prepared by dilution of this stock solution. The samples collected at the start of the exposure (0 h) from additionally prepared test vessels without daphnids and at the end of the exposure (48 h) from vessels with daphnids (pooled replicates) were analyzed via HPLC. A reference substance sodium chloride was used as positive control. The EC50 of the reference substance after 48 hours was determined to be 4.37 g/L. This result was within the range of 3.88 – 7.22 g/L and indicates that the culture of Daphnia magna used in this study was responding normally to toxic stress. The water pH, temperature and dissolved oxygen were within acceptable guideline specifications. The toxicity results presented here were consistent with the results from preliminary tests. Immobilization (mortality) and sublethal effects were observed daily. The analytically determined concentrations of the test substance in the test solutions were within ± 20 % of the nominal concentrations, therefore the effect concentrations can be expressed relative to the nominal concentration for the evaluation of the test substance. The EC50 value was determined to be 9.29 mg test item/L. All reported results refer to the nominal concentrations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.