1,6-Naphthyridine-3-carboxylic acid, 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-1,4-dihydro-2,8-dimethyl-, 2-cyanoethyl ester

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

The test substance melted when approached by the ignition flame.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

CN-ethyl-TH-naphthyridin is classified as a not readily combustible solid and as not flammable solid.

Executive summary:

The test was performed as stipulated in UN test procedure ‘Recommendations on the Transport of Dangerous Goods - Manual of Tests and Criteria’ (UN-MTC), Part III, sub-section 33.2.1.4.1, Test N.1 ‘Test method for readily combustible solids’. CN-ethyl-TH-naphthyridin was formed into a powder train about 250 mm long by 20 mm wide by 10 mm high on a non-combustible, non-porous and low heat-conducting base plate. 30 – 40 mm beyond the 100 mm timing zone, 1 mL of a wetting solution was added to the pile. A hot flame from a gas burner was applied to one end of the powder train until the powder ignites or for a maximum of 2 minutes (5 minutes for powders of metals or metal-alloys). A preliminary screening test was performed to determine if propagation by burning with flame or smoldering occurs without wetted zone. The substance in its delivery state was measured. The test substance melted when approached by the ignition flame. The substance did not burn up. No further testing was required. CN-ethyl-TH-naphthyridin is classified as a not readily combustible solid when tested according to UN-MTC Procedure N.1 and as not flammable solid.

Reference 2

Endpoint:

pyrophoric solids

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is known to be stable in contact with air at room temperature for prolonged periods of time (days) and hence, the classification procedure does not need to be applied

other:

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the organic substance does not contain metals or metalloids and hence, the classification procedure does not need to be applied

Description of key information

a) flammability: Based on a test according to UN N.1 the test substance is not readily combustible and not flammable.

b) pyrophoric properties: The test item did not deliver indications of pyrophoric properties during the realization of other tests. The determination according to UN-MTC Procedure N.2 is not necessary.

c) contact with water: the organic substance does not contain metals or metalloids and hence, the classification procedure does not need to be applied

Key value for chemical safety assessment

Flammability:

not classified