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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 937-417-0 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
The source substance Ashes (residues), when applied to the skin or to the mucous membrane (conjunctivae) of experimental animals, elicited only slight effects at the site of application that disappeared quickly. The substance is not irritant nor sensitizer. Presumably the substance does not enter the body through these routes.
After the acute exposition through the stomach of rats (2000 mg/kg) no digestive tract irritation or other clinical or pathological symptoms were observed. This experiment did not allow the estimation if the substance is absorbed during such an exposition design.
After repeated oral exposure there is some evidence in favour of the substance penetration through stomach mucosa and entering distant compartment of the body a as to pituitary gland, prostate gland or uterus. In reproduction study the effect on fertility indices was detected (increased post-implantation loss and decrease in the number of pups in litter).
The source substance Ashes (residues) could penetrate the body more readily during the inhalation or intratracheal instillation. But also the effects observed in these studies were mostly local influencing the histological structure of pulmonary tissue and the local immune response. The substance is absorbed into blood circulation and influences the blood biochemical and/or haematological parameters. Scarcely the distant effects are reported as those in the bone marrow or the liver. These distant effects are dependent on the physical and chemical constitution of the particulate matter and on the conditions of exposure. But at the optimal conditions the substance could reach also the uterus and elicit negative influence on the foetus development.
Based on the similarity of the source material, Ashes (residues), and the target material, Ashes (residues), nonhazardous municipal solid waste, may be assumed identical or similar toxicokinetic behaviour both materials.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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