Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-729-0 | CAS number: 1369500-14-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2011-07-21 to 2011-08-03 (experimental phase)
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to a relevant guideline without deviations. It was not carried out according to GLP, but it was performed in a test facility which has been certified to be in compliance with the principles of GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Version / remarks:
- adopted March 23, 2006
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Version / remarks:
- amended 23 July 2009
- Deviations:
- no
- GLP compliance:
- no
- Remarks:
- However, the study was performed in a test facility which has been certified to be in compliance with the principles of GLP.
- Type of method:
- gas saturation method
- Temp.:
- 48.8 °C
- Vapour pressure:
- 0.001 Pa
- Remarks on result:
- other: experimentally determined value
- Temp.:
- 59.6 °C
- Vapour pressure:
- 0.005 Pa
- Remarks on result:
- other: experimentally determined value
- Temp.:
- 79.3 °C
- Vapour pressure:
- 0.005 Pa
- Remarks on result:
- other: experimentally determined value
- Temp.:
- 20 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: extrapolated value
- Temp.:
- 25 °C
- Vapour pressure:
- 0 Pa
- Remarks on result:
- other: extrapolated value
- Conclusions:
- The vapour pressure was determined to be 1.7E-05 Pa at 20 °C and 3.8E-05 Pa at 25 °C by extrapolation. The study is considered to be adequate and reliable.
- Executive summary:
The vapour pressure of the test item was determined according to the OECD guideline No. 104, “Vapour Pressure” (2006).
The gas saturation method was chosen for the determination. The test was performed at 79.3, 59.6 and 48.8 °C. The amount of transferred test item in each of the condensation tubes was determined by HPLC analysis and the vapour pressure at the test temperatures was determined. The vapour pressure of the test item at 25 °C and at 20 °C was extrapolated from the obtained vapour pressure curve according to the simplified Clausius-Clapeyron equation and was calculated to be 1.7E-05 Pa at 20 °C and 3.8E-05 Pa at 25 °C.
Reference
Calibration of HPLC system
The r² fit was 0.9999 (optimum 1.0000). This reflects the suitability of the HPLC-system within the calibration range of 4.825 μg/mL to 96.5 μg/mL of the test item.
Trapping efficacy
The trapping efficiency of the test item in the first cooling trap was very good. 100% of the test item was trapped in the first cooling trap.
Results of the Vapour Pressure Determination
Column No. |
Temp. [°C] |
Volume* [mL] |
Amount of test item in trap 1 [µg] |
Amount of test item in trap 2 [µg] |
Total amount of test item [µg] |
Vapour Pressure [Pa] |
Average vapour pressure [Pa] |
1 |
48.78
|
278393 |
28.954 |
0 |
28.954 |
1.1 x 10-3 |
1.22 x 10-3 |
2 |
347650 |
43.389 |
0 |
43.389 |
1.3 x 10-3 |
||
3 |
417249 |
52.369 |
0 |
52.369 |
1.1 x 10-3 |
||
1 |
59.55
|
136740 |
58.960 |
0 |
58.960 |
4.6 x 10-3 |
4.88 x 10-3 |
2 |
169313 |
83.118 |
0 |
83.118 |
5.2 x 10-3 |
||
3 |
201721 |
90.858 |
0 |
90.858 |
4.8 x 10-3 |
||
1 |
79.30
|
288610 |
1331.528 |
0 |
1331.528 |
5.2 x 10-3 |
5.22 x 10-3 |
2 |
358414 |
1645.232 |
0 |
1645.232 |
5.2 x 10-3 |
||
3 |
441278 |
2044.129 |
0 |
2044.129 |
5.2 x 10-3 |
|
*Corrected volume at test temperature
Vapour pressure curve for extrapolation
The logarithm of the measured vapour pressure was fitted against 1/T. The following equation was obtained:
ln(VP) = - 13971.86 · 1/T + 36.68, where
VP: Vapour pressure [Pa]
T: Temperature [K]
The coefficient of determination was r²=0.9985.
Description of key information
1.7E-05 Pa at 20 °C and 3.8E-05 Pa at 25 °C by extrapolation, OECD 104, gas saturation method, Weissenfeld 2011.
Key value for chemical safety assessment
- Vapour pressure:
- 0 Pa
- at the temperature of:
- 20 °C
Additional information
The vapour pressure of the test item was determined according to the OECD guideline No. 104, “Vapour Pressure” (2006).
The gas saturation method was chosen for the determination. The test was performed at 79.3, 59.6 and 48.8 °C. The amount of transferred test item in each of the condensation tubes was determined by HPLC analysis and the vapour pressure at the test temperatures was determined. The vapour pressure of the test item at 25 °C and at 20 °C was extrapolated from the obtained vapour pressure curve according to the simplified Clausius-Clapeyron equation and was calculated to be 1.7E-05 Pa at 20 °C and 3.8E-05 Pa at 25 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.