Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 916-533-5 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
96 hour LC50 84.4 mg/L (95 % confidence limits 52.27 - 162.50), 96 hour NOEC 56.7 mg/L, 96 hour LOEC 128.5 mg/L, OECD 203, EU Method C.1, EPA OPPTS 850.1075, Japanese MAFF (2-7-1), Sipos (2013c).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 84.4 mg/L
Additional information
In the key study (Sipos, 2013c), the acute toxicity of the test material to fish was determined in an acute toxicity study using Cyprinus carpio. The study was performed under GLP conditions and in line with the standardised guidelines OECD 203, EU Method C.1, EPA OPPTS 850.1075, and Japanese MAFF (2-7-1).
Based on the results of the preliminary range-finding test 7 fish per concentration were exposed for 96 hours under semi-static conditions at nominal test material concentrations of 19.1, 34.3, 61.7, 111.1 and 200 mg/L. Corresponding to measure geometric mean concentration of 7.7, 34.4, 56.7, 128.5 and 239.4 mg/L. Since measured values deviated more than 20 % of the nominal, effect parameters were expressed in terms of measured concentrations.
Under the conditions of the test, mortality was observed at measured concentrations of ≥ 128.5 mg/L. No sub-lethal effects were observed during exposure. Based on these results it was possible to calculate the following effect parameters; LC50 84.4 mg/L (95 % confidence limits 52.27 - 162.50 mg/L); NOEC 56.7 mg/L; LOEC 128.5 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.