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EC number: 291-751-5 | CAS number: 90474-13-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1994-11-19 to 1994-12-02
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 995
- Report date:
- 1995
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- Version / remarks:
- and Commission Directive 92/69/EEC (C1, 31st July 1992)
- Deviations:
- no
- GLP compliance:
- yes
Test material
- Reference substance name:
- Diethyl 1,2-cyclopentanedicarboxylate
- EC Number:
- 291-751-5
- EC Name:
- Diethyl 1,2-cyclopentanedicarboxylate
- Cas Number:
- 90474-13-8
- Molecular formula:
- C11H18O4
- IUPAC Name:
- 1,2-diethyl cyclopentane-1,2-dicarboxylate
- Test material form:
- other: liquid
- Details on test material:
- - Name of test material (as cited in study report): 852 DIESTER
- Physical state: liquid
- Analytical purity: 96.8 %
- Purity test date: 1994-11-18
- Lot/batch No.: 878601/007 007/95
- Expiration date of the lot/batch: 1996-10-13
- Storage condition of test material: at room temperature and protected from light
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: the stock solution was prepared by dissolving 100 mg of the test substance directly per litre of LC reconstituted water. Test solutions were prepared by further dilution of the stock solution with water to provide a geometric series of concontrations: 0, 1, 10 and 100 mg/l
- Sampling method and Sample storage conditions before analysis:
At T0 hours, 4 ml samples were taken from each test solution container and frozen at -20°C.
At T72 hours, 1.5 ml samples were taken from all 3 test replicates at each concentration, pooled and frozen. At the same time, 1 ml was taken from each of the controls and the samples pooled and frozen.
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
- Details on test organisms:
- TEST ORGANISM
- Strain: CCAP 276/20
- Source (laboratory, culture collection): Culture Centre of Algae and Protozoa, Institute of Freshwater Ecology, Far Sawrey, Ambleside, Cumbria, LA 22 OLP, UK
- Age of inoculum (at test initiation):
- Method of cultivation: cultured at C.I.T. ; algae is cultivated for 7 days before harvesting for use in a new culture. pH is verified at 7.5 +/- 0.3 ; conductivity is 260 +/- 20 microScm-1 ; temperature is between 21 and 25°C ; Illumination 24 hours per day at approximatively 2000 lux
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 72 h
Test conditions
- Test temperature:
- 22.9-23.5°C
- pH:
- 7.23-8.20
- Nominal and measured concentrations:
- nominal: 1 x 10e4 cells/ml
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 - < 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 72 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 10 - < 100 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 72 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 10 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Remarks:
- test substance concentrations remain > 78 % of the nominal concentration throughout the test
- Conclusions:
- Under our laboratory conditions, the test substance, 852 DIESTER, was toxic to Scenedesmus subspicatus in a static test at 100 mg/l but non-toxic at 1 and 10 mg/l.
The NOEC is calculated to be 10 mg/l
852 DIESTER should not be classified.
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