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EC number: 271-865-1 | CAS number: 68610-44-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- March 09, 2018 - June 11, 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Specific details on test material used for the study:
- - Composition of test material: Sodium-2-ethylhexyliminomonopropionate and Sodium-2-ethylhexyliminodipropionate
- Analytical purity: >=98%
- Purity test date: 13 December 2017
- Lot/batch No.: WI6K21X06-FD2
- Expiration date of the lot/batch: 05 December 2018
- Appearance: White paste
- Storage: At room temperature - Key result
- Remarks on result:
- not determinable
- Conclusions:
- The melting temperature of the test item was tested by DSC. Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 175°C (> 448K). Melting of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no melting temperature.
- Executive summary:
The melting point of the test item was investigated in a GLP-compliant study performed in accordance with EC A.1 method and OECD Guideline No. 102, using Differential Scanning Calorimetry (DSC). Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 175°C (> 448K). Melting of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no melting temperature.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2012-01-20
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Determination has been run according to standardized method but without GLP compliance.
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E 537 – 07
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- other: differential scanning calorimetry
- Remarks on result:
- other: No melting point was detected in the interval -30-300°C. The sample is a paste at room temperature.
- Conclusions:
- No melting point was detected in the interval -30-300°C. The sample is a paste at room temperature.
- Executive summary:
No melting point was detected in the interval -30-300°C. The sample is a paste at room temperature.
Referenceopen allclose all
Preliminary test
Starting at 200°C, the weight of the sample decreased significantly. At 237°C, the sample weight had decreased by 25%. After the experiment, black residue was observed on the lid of the sample container and a black residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item.
Main study
An endothermic peak was observed between 25°C and 175°C. Based on the weight loss observed during the preliminary test, the endothermic effect was due to evaporation of evaporation of impurities including residual water. An endothermic peak was observed starting at 175°C. The endothermic effect was due to reaction and/or decomposition of the test item. After the experiment, an off-white residue remained in the sample container (original colour: white). The change of the colour indicated reaction and/or decomposition of the test item.
Description of key information
The melting point of 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) was investigated in a GLP-compliant study performed in accordance with EC A.1 method and OECD Guideline No. 102, using Differential Scanning Calorimetry (DSC). Reaction and/or decomposition of the test item was observed during DSC experiment at temperatures of > 175°C (> 448K). Melting of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no melting temperature.
Key value for chemical safety assessment
Additional information
The melting point of 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) was investigated in a GLP-compliant study performed in accordance with standard methods, without deviations (Volic, 2018). The study is considered as reliable (Klimisch 1) and was selected as key study for the endpoint.
The endpoint study summary for 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) is linked to study record(s) on the substance itself but also to study record(s) on an analogue substance, a.k.a. Sodium 3-[(2-carboxyethyl)(2-ethylhexyl)amino]propanoate (CAS RN 94441-92-6 / EC 305-318-6). The latter is used as source substance to fill datagaps on 2-Propenoic acid, methyl ester, reaction products with 2-ethyl-1-hexanamine and sodium hydroxide (methanol free) for particular endpoints pertaining to environmental fate, aquatic toxicity and human health toxicity. Several physico-chemical data are thus reported for the source substance (e.g.physical state, melting point, vapour pressure, surface tension, water solubility and n-octanol/water partition coefficient – identified as “supporting studies”) to support the read-across approach (cf. read-across justification document attached in "13 Assessment reports").
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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