Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 252-601-4 | CAS number: 35511-15-0
Endpoint summary
Administrative data
Description of key information
Acute toxicity by oral route
Acute oral toxicity data are not available for methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide.
For the similar substance Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide the following data are available:
• guinea pig, oral LD50 = 5300 mg/kg
• rat, oral LD50 = 4800 mg/kg.
Overall, available data are conclusive but not sufficient for the classification of the substance.
Acute toxicity by inhalation route
Acute inhalation toxicity data are not available for methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide.
For the similar substance Ethyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide the following data is available:
• rat, inhalation LC50 = 1562 mg/m3.
Detailed information on the type of exposure are not available; moreover, detailed information on the duration of exposure is not available.
Overall, available data are inconclusive for the classification of the substance.
Key value for chemical safety assessment
Additional information
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
