Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 234-667-6 | CAS number: 12022-71-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 05 Oct - 24 Oct 2018
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- Iron titanium trioxide
- EC Number:
- 234-667-6
- EC Name:
- Iron titanium trioxide
- Cas Number:
- 12022-71-8
- Molecular formula:
- FeO3Ti
- IUPAC Name:
- 4-oxo-1,3-dioxa-2-ferra-4-titanacyclobutane
- Test material form:
- solid
Constituent 1
Results and discussion
Water solubilityopen allclose all
- Key result
- Water solubility:
- 0.23 mg/L
- Conc. based on:
- element (dissolved fraction)
- Remarks:
- Iron
- Loading of aqueous phase:
- 1 g/L
- Temp.:
- 20 °C
- pH:
- >= 6.8 - <= 7
- Key result
- Water solubility:
- 0.12 mg/L
- Conc. based on:
- element (dissolved fraction)
- Remarks:
- Titanium
- Loading of aqueous phase:
- 1 g/L
- Temp.:
- 20 °C
- pH:
- >= 6.8 - <= 7
- Details on results:
- Preliminary test
Three preliminary tests were carried out with specified amounts of the test item and 100 ml and 500 ml demineralized water, respectively. After each addition of an amount of water, the mixture was stirred for at least 24 hours, and visually checked for any undissolved particles.
The preliminary test showed that the water solubility of the test item is < 10 mg/L. ln this range the water solubility of organic test items should be determined with the column elution method. However as the present test item is an inorganic substance the suitable method according to ECHA guidance R.7a is the flask method with two loading rates.
Flask method
As the test item is an inorganic compound the concentration of lron and Titanium in the water extracts was determined in this study as representative parameters for the solubility of the complete test item.
The main test was performed with two loading rates (0.1 g/l and 1 g/l). Therefore, three flasks (experiment A - C) were prepared with about 10 mg of the test item and 100 ml demineralized water and three flasks (experiment E - G) with about 100 mg of the test item and 100 ml demineralized water, respectively. The batches were stirred for different times at 30°C (experiments A and E for 24 h, experiments B and F for 48 h, experiments C and G for 72 h) in tightly closed flasks.
After equilibration (further stirring for 24 h at 20"C) precipitate was observed in the flasks of the experiments excluding the blank experiment.
One other experiment was performed according to this procedure but without test item ("blank" = D).
All measured lron and Titanium concentrations were at or below the quantification limit of the analytical method for a loading rate of 0.1 g/L.
The mean concentrations for a loading rate of 1.0 g/l were 0.23 mg/l lron and 0.12 mgll Titanium.
The concentrations found in the experiments with different loading rates were in different orders of magnitude for both elements. Therefore a dependency of the loading rate was observed. All results for one loading rate and one element did not differ more than 15 o/o. Therefore the results fulfilled the requirement from guideline OECD 105.
Any other information on results incl. tables
Table 1: Water solubility experiments of the test item (loading rate 1.0 g/L)
Experiment | E | F | G | D (blank) |
amount of test item / g | 127.5 | 103.2 | 112.8 | -- |
amount of demineralized water / mL | 100 | 100 | 100 | 100 |
stirring time at 30 °C / h | 24 | 48 | 72 | 72 |
pH at 25 °C | 6.9 | 6.8 | 7.0 | 6.3 |
measured iron concentration / mg/L | 0.25 | 0.19 | 0.24 | <0.025* |
measured titanium concentration / mg/L | 0.13 | 0.13 | 0.10 | <0.005* |
*indicates below the quantification limit
Applicant's summary and conclusion
- Conclusions:
- The water solubility of the test item at a temperature of 20 °C was determined according to the flask method. The mean concentrations for a loading rate of 1.0 g/lLwere 0.23 mg/L lron and 0.12 mg/L Titanium.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.