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Diss Factsheets
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EC number: 228-567-1 | CAS number: 6297-03-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Hydrolysis
According to Annex VIII, column 2 (9.2.2.1) and Annex XI, section 2 of Regulation (EC) No. 1907/2006 hydrolysis as a function of pH is omitted as the test substance is almost insoluble in water and therefore technically not possible (water solubility < 0.1 mg/L). In addition, as the test item is readily biodegradable this test is not required.
Biodegradation
A study was performed to determine the potential for biodegradation of the test item in water following OECD Test Guideline 301F. After 28 days the test item was degradated to 62 %, due to the very low water solubility the 10-days window was not fulfilled. Nevertheless, the test substance is evaluated as readily biodegradable. Degradation of the reference substance was 86 % after 14 days, therefore validity criteria were fulfilled.
Biodegradation in water, soil and sediment:
According to Annex IX, column 2 (9.2.1) of Regulation (EC) No. 1907/2006, the test and not required as the test item is ultimately biodegradable to > 60 % under conditions of an OECD 301 test (see above). Therefore, it can be concluded that it will readily biodegradable in the environment. Thus, a simulation test for biodegradability in water, soil and sediment is scientifically unjustified.
Bioaccumulation:
A study is not required for this tonnage band. A log Kow of 16.76 was estimated for the molecule, indicating potential for bioaccumulation. However, according to the REACH Guidance Document R11 (PBT Assessment), the BCF of substances with a log Kow of > 10 is probably lower than 2000 L/kg. Due to the lack of experimental data, the assessment of the bioaccumulation potential is evaluated in a weight-of-evidence approach. Estimations of the BCF were performed with three different models. The three separate estimation models (CATALOGIC v5.11.2, BCFBAF v3.01 and T.E.S.T v4.01) calculate maximum BCF values between 3.2 and 78.4. Considering mitigating factors like biotransformation, water solubility and molecular size, there is low potential for bioaccumulation. Especially the very low water solubility exposure of aquatic organisms to significant amounts of test substance is unlikely. Therefore, bioaccumulation under environmental conditions is not expected.
Adsorption/Desorption:
According to Annex XI, 2. of Regulation (EC) No. 1907/2006, testing the adsorption/ desorption coefficient is technically not possible as the test substance is insoluble in water and shows only very poor solubility in organic solvents. When a solution of the test substance in toluene gets in contact with an aqueous phase, the test substance will immediately precipitate. However, one study investigating the adsorption coefficient of a structural similar compound is available (see read across details in IUCLID Section 13). The study was performed according to GLP and OECD 121. The log Koc was determined to be > 4.1 indicating that the adsorption potential is high. The log Koc of the test item is expected to be higher, because of the longer carbon chains. Thus, it can be assumed that the adsorption potential is also high.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.