4,4'-bis(dimethylamino)-4''-(methylamino)trityl alcohol

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

Experimental study performed according to test guidelines

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

flask method

Key result

Water solubility:

14.01 mg/L

Conc. based on:

test mat.

Temp.:

25 °C

Remarks on result:

other: Other details not known

PRELIMINARY TEST AT 96 h

Concentration obtained (mg/L)		Average	Absorbance	Average	Total Dilution factor(if any)	Water Solubility Value by Standard Curve (mg/L)	Average
R1	2.78	2.77	0.42	0.42	10	27.8	27.75
R2	2.77		0.42		10	27.7

CONFIRMATORY TEST AT 24, 48 AND 72 h

Sample stirring (hours)	Concentration obtained		Average	Absorbance	Average	Dilution factor	Water Solubility value obtained (mg/L)	Average
24 h	R1	2.74	2.74	0.42	0.42	5	13.70	13.70
24 h	R2	2.74		0.42			13.70
48 h	R1	2.73	2.73	0.42	0.42	5	13.65	13.68
48 h	R2	2.74		0.42			13.72
72 h	R1	2.93	2.93	0.45	0.45	5	14.65	14.65
72 h	R2	2.93		0.46			14.65

pH

pH
Preliminary Test	Confirmatory Test
96 h	24 h	48 h	72 h
6.89	6.20	6.61	6.21
6.79	6.23	6.23	6.20

Conclusions:

The mean water solubility value of test substance was determined to be 14.01 mg/L

Executive summary:

The study was conducted to determine the solubility of test substance in ultra-pure water, according to the OECD guideline 105 (Adopted by the Council on 27th July 1995) and OECD 101(Adopted: 12 May 1981). Test was conducted at 25±2 °C in two stages; preliminary test for 24/96 h, followed by confirmatory test for 24 h, 48 h and 72 h in replicates. The final water solubility value was calculated based on average of the individual values obtained after 24 h, 48 h and 72 h. The difference between the average values in three vessels was not observed more than 15%. The water solubility value was observed to be 14.01 mg/L at 25±2°C.

Description of key information

The water solubility value of test substance was determined to be 14.01 mg/L

Key value for chemical safety assessment

Water solubility:

14.01 mg/L

at the temperature of:

25 °C

Additional information

The study was conducted to determine the solubility of test substance in ultra-pure water, according to the OECD guideline 105 (Adopted by the Council on 27th July 1995) and OECD 101(Adopted: 12 May 1981). Test was conducted at 25±2°C in two stages; preliminary test for 24/96 h, followed by confirmatory test for 24 h, 48 h and 72 h in replicates. The final water solubility value was calculated based on average of the individual values obtained after 24 h, 48 h and 72 h. The difference between the average values in three vessels was not observed more than 15%. The water solubility value was observed to be 14.01 mg/L at 25±2°C.Thus, on the basis of available information the test chemical was considered to be slightly soluble in water.