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EC number: 204-541-5 | CAS number: 122-40-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Data is from RIFM report, Robust study summaries and authoritive database HSDB and HPVIS
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Principles of method if other than guideline:
- Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal. The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test).
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: (2E)-2-(phenylmethylidene)heptanal
- Molecular formula: C14H18O
- Molecular weight: 202.2952 g/mol
- Smiles notation: c1(\C=C(\CCCCC)C=O)ccccc1
- InChl: 1S/C14H18O/c1-2-3-5-10-14(12-15)11-13-8-6-4-7-9-13/h4,6-9,11-12H,2-3,5,10H2,1H3/b14-11-
- Substance type: Organic
- Physical state: Liquid - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Concentration of sludge: 30 mg/L
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- other: BOD
- Details on study design:
- TEST CONDITIONS
- Other: Bottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l);
Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l);
Bottle 4: Basal culture medium + activated sludge 30 - Reference substance:
- aniline
- Key result
- Parameter:
- other: BOD
- Value:
- 90
- Sampling time:
- 28 d
- Remarks on result:
- other: readily biodegradable
- Details on results:
- Test substance undergoes 90% degradation by BOD parameter in 28 days.
- Results with reference substance:
- Reference substance undergoes 61% degradation in 28 days.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be 90% by BOD parameter in 28 days. Thus, based on percentage degradation, (2E)-2-(phenylmethylidene)heptanal is considered to be readily biodegradable in water.
- Executive summary:
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) under aerobic conditions.The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. Aniline was used as a reference substance for the study. Test vessel involve theBottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l); Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l) and Bottle 4: Basal culture medium + activated sludge 30 mg/l. Reference substance undergoes 61% degradation in 28 days.The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanalwas determined to be 90% by BOD parameter in 28 days.Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
Reference
Description of key information
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) under aerobic conditions (A. M. Api et. al, 2015).The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. Aniline was used as a reference substance for the study. Test vessel involve theBottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l); Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l) and Bottle 4: Basal culture medium + activated sludge 30 mg/l. Reference substance undergoes 61% degradation in 28 days.The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanalwas determined to be 90% by BOD parameter in 28 days.Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
Various experimental studies for the target compound (2E)-2 -(phenylmethylidene)heptanal (CAS No. 122-40-7) were reviewed for the biodegradation end point which are summarized as below:
In an experimental key study from peer reviewed journal (A. M. Api et. al, 2015), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) under aerobic conditions. The study was performed according to OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. Aniline was used as a reference substance for the study. Test vessel involve the Bottle 1 & 2: Basal culture medium + activated sludge 30 mg/l + test chemical (100 mg/l); Bottle 3: Basal culture medium + activated sludge 30mg/l+ aniline (100mg/l) and Bottle 4: Basal culture medium + activated sludge 30 mg/l. Reference substance undergoes 61% degradation in 28 days. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanel was determined to be 90% by BOD parameter in 28 days.Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
In an supporting study from authoritative database (J-CHECK, 2017), biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7).The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I)). Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be 51 and 81% by BOD and TOC removal parameter in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
Another biodegradation study was conducted according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test) under aerobic condition for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7) (HSDB, 2017). Secondary effluent from an unacclimatized activated sludge was used as a test inoculum. 10-day window criteria has been fulfilled. The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be 10 and 65% by CO2 evolution parameter after 10 and 28 days, respectively. Thus, based on percentage degradation, (2E)-2-(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
In an supporting study from peer reviewed journal (A.M. Api et. al, 2015),biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (CAS no. 122-40-7). The study was performed according to OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test). The percentage degradation of test substance (2E)-2 -(phenylmethylidene) heptanal was determined to be 70.5% by CO2 evolution parameter in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be readily biodegradable in nature.
For the target chemical(2E)-2-(phenylmethylidene)heptanal(CAS No. 122-40-7), Biodegradation study was conducted according to Commission Directive 79/831/EWG annex V part C method for 28 days for evaluating the percentage biodegradability of test substance (2E)-2-(phenylmethylidene)heptanal (A.M. Api et. al, 2015). The percentage degradation of test substance (2E)-2-(phenylmethylidene)heptanal was determined to be41% in 28 days. Thus, based on percentage degradation, (2E)-2 -(phenylmethylidene)heptanal is considered to be inherently biodegradable in nature.
On the basis of above results for target chemical (2E)-2 -(phenylmethylidene)heptanal (from peer reviewed journal, authoritative database J-CHECK and HSDB, 2017), it can be concluded that the test substance (2E)-2 -(phenylmethylidene)heptanal can be expected to be readily biodegradable in nature.
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