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Diss Factsheets
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EC number: 200-466-7 | CAS number: 60-27-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- flammable solids
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- test procedure in accordance with generally accepted scientific standards and described in sufficient detail
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method A.10 (Flammability (Solids))
- Principles of method if other than guideline:
- The test methods are described in another document. This does not impair the conclusion of the test results.
The principles of the test methods including their deviations to the guideline are described in detail in the field "any other information on materials and methods". - GLP compliance:
- not specified
- Key result
- Test procedure:
- burning time (test type not further specified)
- Remarks on result:
- other: the substance ignites shortly but terminates quickly
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Creatinine can be ignited but it is melting and burning off calmly. Therefore Creatinine is considered to be not highly flammable.
- Executive summary:
Three tests were conducted according to guidelines similar to guideline A.10.
Creatinine was dried before testing. The dried Creatinine could be ignited by the 1000 °C hot platin wire, which was dipped for 5 seconds into the dried substance. Creatinine was melting, changed its colour into brown and the ignition process was terminated rapidly ("Bewertungszahl 2").
In a second test approx. 200 mg of Creatinine were put into a flat iron bowl and heated with an open gas flame burner for 10 -15 seconds. Creatinine was melting and was deposed but could not be ignited.
In a third test approx. 150 mg Creatinine and a 1:1 mixture of Creatinine with potassium nitrate were put into a red heated iron bowl for 60 seconds. Creatinine itself could not be ignited, but the mixture with potassium nitrate was burning of calmly.
Therefore it is concluded that Creatinine could be ignited but is not highly flammable.
Reference
1. Creatinine could be ignited by the 1000 °C hot platin wire, which was dipped for 5 seconds into the dried substance. Creatinine was melting, changed its colour into brown and the ignition process was terminated rapidly ("Bewertungszahl 2").
2. Creatinine could not be ignited by an open flame hold onto the substance for approx. 10 -15 seconds ("Bewertungszahl 1"). Creatinine was melting and was deposed but could not be ignited.
3. Creatinine could not be ignited when put into a red heated iron bowl for 60 seconds ("Bewertungszahl 1"). A mixture of potasium nitrate and Creatinine was burning off calmly after the same treatment ("Bewertungszahl 2"). "Gesamt-Bewertung: Bewertungszahl 1,5"
Description of key information
Creatinine can be ignited but it is melting and burning off calmly.
Therefore Creatinine is considered to be not highly flammable.
Key value for chemical safety assessment
- Flammability:
- not classified
Additional information
The tests were conducted according to guidelines similar to guideline A.10.
Creatinine was dried before testing. The dried Creatinine could be ignited by the 1000 °C hot platin wire, which was dipped for 5 seconds into the dried substance. Creatinine was melting, changed its colour into brown and the ignition process was terminated rapidly ("Bewertungszahl 2").
In a second test approx. 200 mg of Creatinine were put into a flat iron bowl and heated with an open gas flame burner for 10 -15 seconds. Creatinine was melting and was deposed but could not be ignited.
In a third test approx. 150 mg Creatinine and a 1:1 mixture of Creatinine with potassium nitrate were put into a red heated iron bowl for 60 seconds. Creatinine itself could not be ignited, but the mixture with potassium nitrate was burning of calmly.
Therefore it is concluded that Creatinine could be ignited but is not highly flammable.
Justification for classification or non-classification
Due to the test result Creatinine can be excluded from the hazard class “flammable solids”and does not have to be classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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