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Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Remarks:
- The endpoint was calculated using the PETROTOX model that is made available by CONCAWE and uses hydrocarbon block model to predict eco-toxicological endpoints based on actual analytical information of the intermediate substance
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- The endpoint was calculated using the PETROTOX model that is made available by CONCAWE and uses hydrocarbon block model to predict eco-toxicological endpoints based on actual analytical information of the intermediate substance.
- Justification for type of information:
- The toxicity to aquatic algae and cyanobacteria is determined using valid QSAR model via PETROTOX software based on substance detailed analytical determination. Hydrocarbon blacks are entered into the model to calculate toxicity to Algae and Cyanobacteria.The model uses rich library of CONCAWE physical and chemical properties as well as solubility, octanol-water coefficients and toxicology data of hydrocarbon blocks based on rich collection of study reports.
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 019
- Report date:
- 2019
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Valid QSAR model using PETROTOX software based on actual analytical information of the substance.
- Principles of method if other than guideline:
- The endpoint for the intermediate UVCB substance was calculated using the PETROTOX model that is made available by CONCAWE and uses hydrocarbon block model to predict eco-toxicological endpoints.Hydrocarbon blocks and groups for the model is based on the detailed substance composition and analytical information. This model assumes that complex hydrocarbon mixture exert a narcotic mode of toxic action which is assumed to be additive. The model uses target lipid model and toxic unit theory employing a rich database of physica/chemical properties of hydrocarbons and toxicity studies to calculate the toxicity and environmental risk limits. The model also uses three phase (air-water-free product) oil solubility to calculate the distribution among the exposure water, headspace and free product phases.
- GLP compliance:
- not specified
- Remarks:
- QSAR computational model using PETROTOX
Test material
- Reference substance name:
- Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate
- Molecular formula:
- C5-C29
- IUPAC Name:
- Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate
- Test material form:
- liquid
- Details on test material:
- Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate. It is a complex combination of hydrocarbons as described in section one.
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not required
- Remarks:
- QSAR computational model using PETROTOX
Test organisms
- Test organisms (species):
- Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Study design
- Total exposure duration:
- 72 h
Results and discussion
Effect concentrations
- Key result
- Duration:
- 72 h
- Dose descriptor:
- other: LL50 / NOEL
- Remarks:
- standard output from PETROTOX which is equivalent to LC50
- Effect conc.:
- ca. 464.53 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- not specified
- Details on results:
- The output of the PETROTOX model gives LL50/NOEL and Toxicity Unit (TU) at different loadings considering 10% headspace. The intercept of the test species ( Desmodesmus subspicatus ) is considered as 221,0 micromol / g octanol and default 0 mg/l particulate organic carbon loading for bioavailability mode for algae and SSTP organisms.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Conclusions:
- The LL50/NOEL of the UVCB intermediate substance that is combination of hydrocarbons to aquatic algae and cynobacteria (Desmodesmus subspicatus) was estimated to be 464,53 mg/L using PETROTOX model based on actual analytical information of the intermediate substance.
- Executive summary:
The acute toxicity to aquatic algae and cyanobacteria from the intermediate UVCB substance (Hydrocarbons from mixed waste plastics, thermo-mechanical depolymerization condensate) was calculated using the PETROTOX model that is made available by CONCAWE and uses hydrocarbon block model to predict eco-toxicological endpoints.Hydrocarbon blocks and groups for the model is based on the detailed substance composition and analytical information. This model assumes that complex hydrocarbon mixture exert a narcotic mode of toxic action which is assumed to be additive. The model uses target lipid model (TLM) and toxic unit theory employing a rich database of physical/chemical properties of hydrocarbons and toxicity studies to calculate the toxicity and environmental risk limits. The model also uses three phase (air-water-free product) oil solubility to calculate the distribution among the exposure water, headspace and free product phases at different product loadings. The headspace is set as 10% to account for volatilization of some components. Additionally, the particulate organic carbon (POC) loading was set at default 0 mg/l for algae and SSTP organisms. It is assumed that the presence of POC would result in the absorption of some of the test substance and hence lower bioavailability. The output of the PETROTOX model gives 464,53 mg/L as LL50/NOEL.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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