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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20 sept 2017 to 04 October 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
The determination was carried out using a flask method designed to be compatible with the data endpoint of Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
The test system consisted of purified water.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
Hexahydrocyclopenta[c]pyrrol-2(1H)-amine
EC Number:
259-201-9
EC Name:
Hexahydrocyclopenta[c]pyrrol-2(1H)-amine
Cas Number:
54528-00-6
Molecular formula:
C7H14N2
IUPAC Name:
octahydrocyclopenta[c]pyrrol-2-amine
Test material form:
liquid
Remarks:
Colourless
Specific details on test material used for the study:
Batch 18131263

Results and discussion

Water solubility
Temp.:
20 °C
pH:
> 10.6 - < 11
Remarks on result:
completely miscible
Details on results:
Due to the miscibility of the test item with water, the standard regulatory approach of preparation and analysis of saturated solutions of test item in water was neither valid nor feasible. Therefore miscibility was demonstrated over a significant range of concentrations, at the required test temperature of 20.0 ± 0.5 °C, to satisfy the regulatory endpoint of water solubility addressed by the regulatory methods.

Applicant's summary and conclusion

Conclusions:
The test item was determined to be miscible with water, in all proportions, at 20.0 ± 0.5 °C.
Executive summary:

The test item was determined to be miscible with water, in all proportions, at 20.0 ± 0.5 °C.