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EC number: 306-523-3 | CAS number: 97281-24-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17 Oct - 14 Nov 2006
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- non-GLP, no purity
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: Activated sludge from the aeration tank of a municipal wastewater treatment plant, ARA Werdhölzli, Zürich, Switzerland (11 Oct 2006)
- Pretreatment: Prior to the test the sludge was washed twice tap water. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 10 - 20 mg/L
- Based on:
- other: TOC
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Details on study design:
- TEST CONDITIONS
- Composition of medium: Aerobic mineral salts medium prepared with deionised water
- Test temperature: 22 ± 0.5 °C
- pH adjusted: Yes, the pH-value was checked at the beginning and at the end of the test and adjusted to pH 7.4 (± 0.2) with NaOH or HCl.
- Suspended solids concentration: 30 mg/L
- Continuous darkness: Yes, temperature-controlled dark room
TEST SYSTEM
- Culturing apparatus: 2500 mL closed bottle containing a total volume of test solution of 2000 mL
- Number of culture flasks/concentration: 2/concentration
- Method used to create aerobic conditions: Aerated with synthetic CO2-free air for a maximum test period of 28 days.
- Measuring equipment: Shimadzu 5050 TOC-Analyzer using the NPOC-mode for DOC-determination
- Details of trap for CO2: The air leaving the individual vessels was passed through gas-absorption bottles filled with NaOH.
SAMPLING
- Sampling frequency: on day 0, 1, 3, 7, 10, 14, 21, 24 and 28
- Sampling method: Samples were centrifuged (15 min at 4500g) and acidified to pH<2. Prior to analysis the samples were sparged with CO2-free
high purity air for 10 min to remove inorganic carbon.
CONTROL AND BLANK SYSTEM
- Inoculum blank: yes, 2 vessels
- Abiotic sterile control: no
- Toxicity control: no
- Other: yes, procedure control, 1 vessels - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 79.4
- Sampling time:
- 28 d
- Remarks on result:
- other: Mean of two replicates
- Results with reference substance:
- The reference substance reached 94% biodegradation after 14 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Reference
The test substance is readily biodegradable under conditions tested. The biodegradation was > 60% after 28 days and the 10 -day-window was fulfilled, because the biodegradation reached 65% at the end of the 10 -day-window.
Percentage biodegradation of test substance (mean oft two replicates) and reference substance
Day |
Test substance (% degradation) |
Reference substance (% degradation) |
||
Test unit no. 1 |
Test unit no. 2 |
Mean degradation |
||
0 |
0.0 |
0.0 |
0.0 |
0.0 |
1 |
0.0 |
-0.7 |
-0.4 |
3.3 |
3 |
9.3 |
4.7 |
7.0 |
46.3 |
7 |
46.7 |
33.7 |
40.2 |
78.8 |
10 |
53.7 |
56.2 |
54.9 |
93.9 |
14 |
64.9 |
68.3 |
66.6 |
93.5 |
21 |
69.1 |
77.4 |
73.2 |
98.3 |
24 |
74.1 |
79.1 |
76.6 |
96.4 |
28 |
75.8 |
83.0 |
79.4 |
98.2 |
Description of key information
Readily biodegradable: 79.4% (CO2 evolution) after 28 d (OECD 301B)
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One experimental study is available investigating the ready biodegradability of Fatty acids, C8-10 (even numbered), diesters with neopentyl glycol and di- and triesters with trimethylolpropane (Oleon, 2006). The study was conducted according to OECD 301B using non-adapted activated sludge from a municipal sewage treatment plant. After 28 d a biodegradation of 79.4% (O2 consumption) was recorded. The 10-day window was met and the substance is considered to be readily biodegradable according to the OECD criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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