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EC number: 417-070-7
CAS number: 151006-62-1
1-DODECENE TRIMER, HYDROGENATED; ALKANE 4
Poly alpha olefins and their respective
structural analogues were not acutely toxic when administered via oral
or dermal routes in several animal studies. Hence, these substances do
not meet the classification and labelling criteria for acute oral or
dermal toxicants as defined by CLP EU Regulation 1272/2008 (GHS aligned)
criteria; therefore DNELs were not derived for these endpoints.
In the studies that concluded an LC50 of
lower than 5 mg/L, deaths can be attributed entirely to chemical
pneumonitis, with the primary reported effects being reported being dark
red lung tissue. The concentrations required to achieve these results do
not represent a realistic scenario of how PAOs would behave in normal
atmospheric conditions. The key value for vapour pressure given for PAOs
is 1.889 Pa. This is so low that PAOs are not expected to volatilise and
thus, an acute toxicity inhalation hazard is not deemed to be relevant.
Therefore, DNELs have not been derived.
classification and labeling for aspiration toxicity relies on the
measured or calculated kinematic viscosity of a substance at 40°C rather
than results from toxicological studies with animals. The reported
kinematic viscosity value for dec-1-ene dimers, hydrogenated is 5.1 cSt
(Chevron Phillips Chemical Company, 2002). This value meets the criteria
for classification as an aspiration toxicant under EU CLP (< 20.5 cSt)
regulations. Dec-1-ene dimers, hydrogenated is classified as a Category
1 aspiration toxicant under EU CLP regulation 1272/2008 (GHS aligned). A
DNEL is neither feasible nor appropriate for this endpoint.
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