Registration Dossier

Administrative data

First-aid measures

Eye Contact:
Immediately flush eyes with copious amounts of water for at least 15 minutes. If irritation persists, seek medical attention.

Skin Contact:
After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly
careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before
reusing.

Inhalation:
Allow the victim to rest in a well ventilated area. Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or waistband. If
breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth resuscitation. In severe cases or if symptoms persists, seek medical attention.

Ingestion:
Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. If symptoms appears,
seek immediate medical attention

Fire-fighting measures

Extinguishing media:
In case of fire use water, chemical type foam, carbon dioxide, dry chemical. Prevent run off of water from entering drains

Hazardous combustion products:
The substance evolves toxic fumes due to the presence of CO, CO2, NOx

Fire-fighting equipment:
Respiratory and eye protection for fire-fighting personnel

Accidental release measures

Person-related safety precautions:
- Wear protective equipment
- Keep unprotected persons away

Measures for cleaning / collecting:
- Damp down to avoid dust generation
- Do not allow to enter public sewers and watercourses
- Sweep or shovel-up spillage and remove to a safe place
- Absorb spillage in earth or sand

Handling and storage

- This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should
take into account the fire, health and chemical hazard data given on this dossier.
- It should always be handled in an efficient fume hood or equivalent system and, if necessary, wear protective equipment.
- Care should be taken to prevent the chemical from coming into contact with the skin or eyes and from contaminating personal clothing.
- Keep in unopened containers in a cool, dry and well ventilated place.
- This material should be handled and stored per label instructions to ensure product integrity.
- Avoid contact with oxidizing substances

Transport information

Land transport (ADR/RID)

UN number:
2811
Shippingopen allclose all
Class:
6.1
Classification code:
TOXIC SOLID, ORGANIC, N.O.S. (Theophylline)
Packaging group:
III
SpecialProvisionsopen allclose all

Inland waterway transport (ADN(R))

UN number:
2811
Shippingopen allclose all
Class:
6.1
Classification code:
TOXIC SOLID, ORGANIC, N.O.S. (Theophylline)
Packaging group:
III
Remarksopen allclose all

Marine transport (IMDG)

UN number:
2811
Proper shipping name and description:
TOXIC SOLID, ORGANIC, N.O.S. (Theophylline)
Chemical name:
Theophylline
Class:
6.1
Packaging group:
III
Remarksopen allclose all

Air transport ICAO/IATA

UN number:
2811
Proper shipping name and description:
TOXIC SOLID, ORGANIC, N.O.S. (Theophylline)
Chemical name:
Theophylline
Class:
6.1
Packaging group:
III
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Eye/face protection
Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH
(US) or EN 166(EU).

Hand protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product.
Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.The selected protective gloves have to
satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Skin and body protection
The type of protective equipment (es. Tyvek suit) must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
Complete suit protecting against chemicals, flame retardant antistatic protective clothing.

Respiratory protection
Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N99 (US) or type P2 (EN 143) with cartridges P1 (inert
substances) P2 (harmful substances) P3 (toxic substances). Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Stability and reactivity

Hazardous polimerization not occurs
Conditions to avoid: heat, flames and sparks
Incompatible materials: strong oxidising agents
The product is stable at room temperature and in usual working conditions
Hazardous decomposition products: the substance evolves toxic fumes due to the presence of CO, CO2, NOx.

Disposal considerations

Do not empty into drains. Use appropriate containment to avoid environmental contamination. Disposal should be in accordance with local, state or national regulation
Wastes have to be disposed in a site approved for chemical and hazardous waste or burned in a specialized burning centre