Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 420-380-5
CAS number: 136465-81-1
The 24, 48, 72 and 96 hour median lethal concentrations (LC50) of
PTH-Decahydroamide to the freshwater fish, rainbow trout (Oncorhynchus
mykiss previously known as Salmo gairdneri) were determined under static
test conditions at a temperature of 15 ± 1 °C. The 96 hour LC50 = 68 mg
PTH-Decahydroamide/litre with 95% confidence intervals of 57 to 84 mg/L. The
highest test concentration causing no mortality within the period of the
test was 32 mg/L. The lowest that caused 100% mortality within the
period of the test was 100 mg/L.
The 24 and 48 hour EC50 values of PTH-Decahydroamid to Daphnia magna
were determined under static test conditions at a temperature of 20 ± 1
°C. The 48 hour EC50 was 45 mg PTH-Decahydroamid/litre with 95%
confidence intervals of 33 to 65 mg/L. The highest nominal test
concentration causing no immobility was 5.6 mg/L and the lowest that
caused 100% immobility was 180 mg/L.
The toxicity of the test substance to aquatic algae was determined using
OECD method 201. It was determined that PTH-Decahydroamide (Ro
31-9373/000) inhibited cell growth and reduced growth rate of Scenedesmus
subspicatus significantly under the conditions of the present study
at nominally 10 mg/l and higher. The inhibition rates were estimated for
both the algal biomass b and the growth rate R after 72 hours test
duration; based on nominal concentrations.
EbC50 (0-72 h) 46 mg/l
ERC50 (0-72 h) 74 mg/l
The NOEC was 4.8 mg/l for both cell growth inhibition and growth rate
reduction when based on nominal concentrations. Since this concentration
was below the detection limit of PTH-decahydroamide (Ro 31-9373/000) in
water samples, no actual concentration could be determined.
No significant inhibition in respiration rate of the sludge (> 10 %) was
recorded at 100 mg PTH-decahydroamide (Ro 31-9373/000) per litre. Thus
under the conditions of the test PTH-decahydroamide (Ro 31-9373/ 000)
was not toxic to waste water bacteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again